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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFAP2A
All Species:
22.73
Human Site:
S105
Identified Species:
55.56
UniProt:
P05549
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05549
NP_001027451.1
437
48062
S105
G
Q
R
Q
S
Q
E
S
G
L
L
H
T
H
R
Chimpanzee
Pan troglodytes
XP_001166719
439
48303
S107
G
Q
R
Q
S
Q
E
S
G
L
L
H
T
H
R
Rhesus Macaque
Macaca mulatta
XP_001089006
689
75199
S357
G
Q
R
Q
S
Q
E
S
G
L
L
H
T
H
R
Dog
Lupus familis
XP_848968
437
47999
S105
G
Q
R
Q
S
Q
E
S
G
L
L
H
T
H
R
Cat
Felis silvestris
Mouse
Mus musculus
P34056
437
47952
S105
G
Q
R
Q
S
Q
E
S
G
L
L
H
T
H
R
Rat
Rattus norvegicus
P58197
437
47928
S105
G
Q
R
Q
S
Q
E
S
G
L
L
H
T
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514207
437
47981
A105
A
Q
R
Q
S
Q
E
A
G
L
L
H
T
H
R
Chicken
Gallus gallus
NP_990425
437
47967
P105
G
Q
R
Q
S
Q
E
P
S
L
L
H
A
H
R
Frog
Xenopus laevis
Q2T9K2
434
47032
A105
P
R
S
R
P
E
E
A
G
L
L
S
Q
T
H
Zebra Danio
Brachydanio rerio
Q6P0E7
423
45495
D100
S
Q
R
S
R
S
E
D
A
G
L
L
S
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
58.4
99
N.A.
98.8
98.4
N.A.
97.9
93.5
67
59.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
61.5
99.5
N.A.
99.3
98.8
N.A.
98.8
96.3
79.4
75.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
80
53.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
20
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
100
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
70
0
0
0
0
0
0
0
80
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
80
0
80
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
90
100
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
90
0
80
0
80
0
0
0
0
0
0
10
10
0
% Q
% Arg:
0
10
90
10
10
0
0
0
0
0
0
0
0
0
80
% R
% Ser:
10
0
10
10
80
10
0
60
10
0
0
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
70
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _