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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT18
All Species:
4.55
Human Site:
S110
Identified Species:
12.5
UniProt:
P05783
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05783
NP_000215.1
430
48058
S110
T
E
N
R
R
L
E
S
K
I
R
E
H
L
E
Chimpanzee
Pan troglodytes
A5A6M0
432
48102
V114
E
A
N
T
E
L
E
V
K
I
R
D
W
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001100009
430
48043
S110
T
E
N
R
R
L
E
S
K
I
R
E
H
L
E
Dog
Lupus familis
XP_534794
431
48220
M111
A
D
N
Q
R
L
E
M
K
I
R
E
H
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P05784
423
47520
E109
S
K
I
R
E
H
L
E
K
K
G
P
Q
G
V
Rat
Rattus norvegicus
Q5BJY9
423
47743
E109
S
K
I
R
E
Y
L
E
K
R
G
P
Q
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6PVZ1
467
50967
V139
E
A
N
T
D
L
E
V
K
I
R
E
W
Y
K
Frog
Xenopus laevis
P08802
428
47452
V109
S
A
N
K
K
L
E
V
Q
I
R
Q
H
T
E
Zebra Danio
Brachydanio rerio
Q7ZTS4
431
48612
L114
Q
A
N
S
K
L
E
L
K
I
R
E
A
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.6
99
88.8
N.A.
86.9
84.8
N.A.
N.A.
44.9
60.4
54.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
64.5
100
95.1
N.A.
93
92.7
N.A.
N.A.
60.8
80
71.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
73.3
N.A.
13.3
13.3
N.A.
N.A.
46.6
46.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
100
86.6
N.A.
26.6
26.6
N.A.
N.A.
53.3
80
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
45
0
0
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
12
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
23
23
0
0
34
0
78
23
0
0
0
56
0
0
56
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
23
0
0
23
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
45
0
0
% H
% Ile:
0
0
23
0
0
0
0
0
0
78
0
0
0
0
0
% I
% Lys:
0
23
0
12
23
0
0
0
89
12
0
0
0
0
12
% K
% Leu:
0
0
0
0
0
78
23
12
0
0
0
0
0
45
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
78
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% P
% Gln:
12
0
0
12
0
0
0
0
12
0
0
12
23
0
12
% Q
% Arg:
0
0
0
45
34
0
0
0
0
12
78
0
0
0
0
% R
% Ser:
34
0
0
12
0
0
0
23
0
0
0
0
0
0
0
% S
% Thr:
23
0
0
23
0
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _