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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT8
All Species:
8.79
Human Site:
S453
Identified Species:
19.33
UniProt:
P05787
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05787
NP_002264.1
483
53704
S453
G
A
G
S
S
S
F
S
R
T
S
S
S
R
A
Chimpanzee
Pan troglodytes
A5A6N0
469
51395
N439
L
G
G
T
M
G
S
N
A
L
S
F
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001099707
483
53642
S453
G
A
G
S
S
S
F
S
R
T
S
S
S
R
A
Dog
Lupus familis
XP_854246
451
50349
R422
G
P
G
G
S
F
S
R
S
S
S
S
K
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P11679
490
54547
N459
F
G
S
A
G
G
S
N
T
F
S
R
T
T
K
Rat
Rattus norvegicus
Q10758
483
54000
S453
F
G
S
V
G
G
S
S
T
Y
S
R
T
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507306
467
52824
L432
G
F
N
G
R
D
F
L
Q
P
I
I
P
P
A
Chicken
Gallus gallus
O93532
492
53785
A461
R
G
G
L
A
L
G
A
G
M
G
S
G
A
L
Frog
Xenopus laevis
P08776
502
55661
Y461
G
Y
G
G
G
Y
S
Y
S
S
N
V
S
S
Y
Zebra Danio
Brachydanio rerio
Q6NWF6
520
57741
Y477
G
G
G
Y
S
G
G
Y
S
G
G
Y
S
S
G
Tiger Blowfish
Takifugu rubipres
NP_001011879
553
61247
A496
V
S
A
Q
E
A
T
A
M
E
H
I
N
K
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.6
98.9
77
N.A.
89.5
89.8
N.A.
67
65.2
68.7
63.8
53.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.7
99.5
83.4
N.A.
94.6
95.6
N.A.
80.7
76.6
83.2
77.8
68.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
33.3
N.A.
6.6
20
N.A.
20
13.3
20
26.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
40
N.A.
26.6
33.3
N.A.
26.6
26.6
33.3
26.6
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
10
10
10
0
19
10
0
0
0
0
19
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
19
10
0
0
0
10
28
0
0
10
0
10
0
0
0
% F
% Gly:
55
46
64
28
28
37
19
0
10
10
19
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
19
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
19
10
% K
% Leu:
10
0
0
10
0
10
0
10
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
19
0
0
10
0
10
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
10
0
0
10
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
10
0
0
10
19
0
0
19
0
19
0
% R
% Ser:
0
10
19
19
37
19
46
28
28
19
55
37
46
28
10
% S
% Thr:
0
0
0
10
0
0
10
0
19
19
0
0
19
10
10
% T
% Val:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
10
0
19
0
10
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _