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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT8 All Species: 31.82
Human Site: T67 Identified Species: 70
UniProt: P05787 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05787 NP_002264.1 483 53704 T67 M G G I T A V T V N Q S L L S
Chimpanzee Pan troglodytes A5A6N0 469 51395 T67 G A G I R E V T I N Q S L L A
Rhesus Macaque Macaca mulatta XP_001099707 483 53642 T67 M G G I T A V T V N Q S L L S
Dog Lupus familis XP_854246 451 50349 F66 I N S L N N K F A S F I N K F
Cat Felis silvestris
Mouse Mus musculus P11679 490 54547 T73 V G G I T A V T V N Q S L L S
Rat Rattus norvegicus Q10758 483 54000 T67 V G G I T A V T V N Q S L L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507306 467 52824 L68 S L L A P L N L Q I D P T F Q
Chicken Gallus gallus O93532 492 53785 T90 S A G I Q E V T V N Q N L L T
Frog Xenopus laevis P08776 502 55661 S75 S A G I T S V S V N Q S L L A
Zebra Danio Brachydanio rerio Q6NWF6 520 57741 T91 V A P I Q A V T V N K S L L A
Tiger Blowfish Takifugu rubipres NP_001011879 553 61247 T110 V A P I T A V T V N K S L L A
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.6 98.9 77 N.A. 89.5 89.8 N.A. 67 65.2 68.7 63.8 53.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 73.7 99.5 83.4 N.A. 94.6 95.6 N.A. 80.7 76.6 83.2 77.8 68.5 N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 100 0 N.A. 93.3 86.6 N.A. 0 60 66.6 60 66.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 73.3 100 20 N.A. 100 100 N.A. 0 73.3 86.6 80 86.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 46 0 10 0 55 0 0 10 0 0 0 0 0 37 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 10 0 0 10 10 % F
% Gly: 10 37 64 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 82 0 0 0 0 10 10 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 19 0 0 10 0 % K
% Leu: 0 10 10 10 0 10 0 10 0 0 0 0 82 82 0 % L
% Met: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 10 10 0 0 82 0 10 10 0 10 % N
% Pro: 0 0 19 0 10 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 19 0 0 0 10 0 64 0 0 0 10 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 0 10 0 0 10 0 10 0 10 0 73 0 0 28 % S
% Thr: 0 0 0 0 55 0 0 73 0 0 0 0 10 0 10 % T
% Val: 37 0 0 0 0 0 82 0 73 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _