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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL1
All Species:
25.45
Human Site:
T128
Identified Species:
50.91
UniProt:
P05976
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05976
NP_524144.1
194
21145
T128
S
N
N
K
D
Q
A
T
Y
E
D
F
V
E
G
Chimpanzee
Pan troglodytes
XP_516064
192
20956
T126
S
N
N
K
D
Q
A
T
Y
E
D
F
V
E
G
Rhesus Macaque
Macaca mulatta
XP_001114310
209
22842
T143
A
K
N
R
D
Q
G
T
Y
E
D
Y
L
E
G
Dog
Lupus familis
XP_536054
194
21075
T128
S
N
N
K
D
Q
G
T
Y
E
D
F
V
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P05977
188
20576
G122
S
N
N
K
D
Q
G
G
Y
E
D
F
V
E
G
Rat
Rattus norvegicus
P02600
189
20661
G123
S
N
N
K
D
Q
G
G
Y
E
D
F
V
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508347
153
17011
S87
S
N
N
K
D
Q
G
S
Y
E
D
F
V
E
G
Chicken
Gallus gallus
P02604
192
20880
T126
A
N
N
K
D
Q
G
T
F
E
D
F
V
E
G
Frog
Xenopus laevis
NP_001080252
190
20833
S124
A
N
N
K
D
Q
G
S
F
E
D
F
V
E
G
Zebra Danio
Brachydanio rerio
NP_001005955
151
16919
E87
N
K
D
Q
G
S
F
E
D
F
V
E
G
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54357
147
16595
E87
D
T
A
D
D
F
I
E
G
L
R
H
F
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53014
153
17126
G88
T
Y
A
D
F
Y
E
G
L
K
V
F
D
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
65
97.4
N.A.
91.7
92.7
N.A.
69.5
86
80.4
59.7
N.A.
41.7
N.A.
34.5
N.A.
Protein Similarity:
100
98.9
77.9
98.4
N.A.
95.3
95.8
N.A.
74.7
92.7
90.2
67.5
N.A.
53
N.A.
49.4
N.A.
P-Site Identity:
100
100
60
93.3
N.A.
86.6
86.6
N.A.
86.6
80
73.3
0
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
86.6
93.3
N.A.
86.6
86.6
N.A.
93.3
93.3
93.3
20
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
17
0
0
0
17
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
17
84
0
0
0
9
0
75
0
9
9
0
% D
% Glu:
0
0
0
0
0
0
9
17
0
75
0
9
0
75
9
% E
% Phe:
0
0
0
0
9
9
9
0
17
9
0
75
9
0
0
% F
% Gly:
0
0
0
0
9
0
59
25
9
0
0
0
9
0
75
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
67
0
0
0
0
0
9
0
0
0
9
9
% K
% Leu:
0
0
0
0
0
0
0
0
9
9
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
67
75
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
75
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% R
% Ser:
50
0
0
0
0
9
0
17
0
0
0
0
0
0
0
% S
% Thr:
9
9
0
0
0
0
0
42
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
17
0
67
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
0
0
59
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _