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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYL1 All Species: 46.67
Human Site: Y184 Identified Species: 93.33
UniProt: P05976 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05976 NP_524144.1 194 21145 Y184 D S N G C I N Y E A F V K H I
Chimpanzee Pan troglodytes XP_516064 192 20956 Y182 D S N G C I N Y E A F V K H I
Rhesus Macaque Macaca mulatta XP_001114310 209 22842 Y199 D S N G C I N Y E A F L K H I
Dog Lupus familis XP_536054 194 21075 Y184 D S N G C I N Y E A F V K H I
Cat Felis silvestris
Mouse Mus musculus P05977 188 20576 Y178 D S N G C I N Y E A F V K H I
Rat Rattus norvegicus P02600 189 20661 Y179 D S N G C I N Y E A F V K H I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508347 153 17011 Y143 D S N G C I N Y E A F V K H I
Chicken Gallus gallus P02604 192 20880 Y182 D S N G C I N Y E A F V K H I
Frog Xenopus laevis NP_001080252 190 20833 Y180 D S N G C I N Y E A F V K H I
Zebra Danio Brachydanio rerio NP_001005955 151 16919 Y141 D A N G C I N Y E A F V R H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54357 147 16595 Y137 D Q Q G N I N Y E E F V R M V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P53014 153 17126 Y137 D G E G M V K Y E D F I K K V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 65 97.4 N.A. 91.7 92.7 N.A. 69.5 86 80.4 59.7 N.A. 41.7 N.A. 34.5 N.A.
Protein Similarity: 100 98.9 77.9 98.4 N.A. 95.3 95.8 N.A. 74.7 92.7 90.2 67.5 N.A. 53 N.A. 49.4 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 100 100 100 86.6 N.A. 53.3 N.A. 40 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 66.6 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 84 0 0 0 0 0 % A
% Cys: 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 100 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 100 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % F
% Gly: 0 9 0 100 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 84 0 % H
% Ile: 0 0 0 0 0 92 0 0 0 0 0 9 0 0 84 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 84 9 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 84 0 9 0 92 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % R
% Ser: 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 84 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _