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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HPN All Species: 15.15
Human Site: T9 Identified Species: 47.62
UniProt: P05981 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05981 NP_002142.1 417 45011 T9 A Q K E G G R T V P C C S R P
Chimpanzee Pan troglodytes XP_001157575 402 43325 T9 A Q K E G G R T V P C C S R P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541697 417 44886 T9 A E K E G A R T V P C C S G P
Cat Felis silvestris
Mouse Mus musculus O35453 436 46769 T28 Q P G K G G R T A A C C S R P
Rat Rattus norvegicus Q05511 416 44908 T8 M A K E G G R T A P C C S R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511505 476 51820 Q28 S V P E E E L Q A A E I P F S
Chicken Gallus gallus XP_425558 557 61421 P67 I S I T E D G P P V P E I Q F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001091657 423 46717 G10 E K K V G R P G M S I F S P C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 N.A. 94.7 N.A. 83.9 88.4 N.A. 32.9 30.3 N.A. 51 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.4 N.A. 96.4 N.A. 88.3 92.3 N.A. 47.2 45 N.A. 66.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 80 N.A. 60 80 N.A. 6.6 0 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 86.6 N.A. 66.6 80 N.A. 13.3 6.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 13 0 0 0 13 0 0 38 25 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 63 63 0 0 13 % C
% Asp: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % D
% Glu: 13 13 0 63 25 13 0 0 0 0 13 13 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 13 0 13 13 % F
% Gly: 0 0 13 0 75 50 13 13 0 0 0 0 0 13 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 0 13 0 0 0 0 0 0 0 13 13 13 0 0 % I
% Lys: 0 13 63 13 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % L
% Met: 13 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 13 13 0 0 0 13 13 13 50 13 0 13 13 63 % P
% Gln: 13 25 0 0 0 0 0 13 0 0 0 0 0 13 0 % Q
% Arg: 0 0 0 0 0 13 63 0 0 0 0 0 0 50 0 % R
% Ser: 13 13 0 0 0 0 0 0 0 13 0 0 75 0 13 % S
% Thr: 0 0 0 13 0 0 0 63 0 0 0 0 0 0 0 % T
% Val: 0 13 0 13 0 0 0 0 38 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _