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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UROD All Species: 35.15
Human Site: S219 Identified Species: 77.33
UniProt: P06132 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06132 NP_000365.3 367 40787 S219 Q A L Q L F E S H A G H L G P
Chimpanzee Pan troglodytes XP_513127 367 40740 S219 Q A L Q L F E S H A G H L G P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532602 364 40465 A218 A Q L F E S H A G H L G P Q L
Cat Felis silvestris
Mouse Mus musculus P70697 367 40673 S219 Q A L Q L F E S H A G H L G T
Rat Rattus norvegicus P32362 364 40434 S216 Q A L Q L F E S H A G H L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422430 416 46062 S267 Q A L Q L F E S H A G H L G P
Frog Xenopus laevis NP_001085981 367 41311 S220 Q A L Q V F E S H A G C L G P
Zebra Danio Brachydanio rerio Q9PTS2 369 41626 S221 Q A L Q V F E S H T G C L G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V595 356 39970 S214 Q M L Q V F E S S A E H L S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784308 368 41150 S217 Q L L Q V F D S H A G A L G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32347 362 41331 S215 Q I L Q V F E S W G G E L S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 92.9 N.A. 92.9 89.3 N.A. N.A. 67.5 70.8 67.7 N.A. 52.5 N.A. N.A. 59.7
Protein Similarity: 100 99.7 N.A. 96.7 N.A. 95.6 94 N.A. N.A. 78.3 84.7 83.7 N.A. 67.3 N.A. N.A. 74.7
P-Site Identity: 100 100 N.A. 6.6 N.A. 93.3 93.3 N.A. N.A. 100 86.6 80 N.A. 60 N.A. N.A. 66.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 93.3 93.3 N.A. N.A. 100 93.3 86.6 N.A. 66.6 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 67.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 64 0 0 0 0 0 10 0 73 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 82 0 0 0 10 10 0 0 0 % E
% Phe: 0 0 0 10 0 91 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 10 82 10 0 73 0 % G
% His: 0 0 0 0 0 0 10 0 73 10 0 55 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 100 0 46 0 0 0 0 0 10 0 91 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 46 % P
% Gln: 91 10 0 91 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 0 91 10 0 0 0 0 19 19 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % T
% Val: 0 0 0 0 46 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _