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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UROD All Species: 36.97
Human Site: T141 Identified Species: 81.33
UniProt: P06132 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06132 NP_000365.3 367 40787 T141 V F Q A I T L T R Q R L A G R
Chimpanzee Pan troglodytes XP_513127 367 40740 T141 V F Q A I T L T R Q R L A G R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532602 364 40465 T141 V F Q A I T L T R Q R L A G R
Cat Felis silvestris
Mouse Mus musculus P70697 367 40673 T141 V F Q A I T L T R Q R L A G R
Rat Rattus norvegicus P32362 364 40434 T138 V F Q A I T L T R Q Q L A G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422430 416 46062 T189 V F Q A I T L T R H S L E G K
Frog Xenopus laevis NP_001085981 367 41311 T142 V F R A I T L T R H K I E G K
Zebra Danio Brachydanio rerio Q9PTS2 369 41626 T143 V F K A I T L T R H K I E G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V595 356 39970 M136 V G D A I T M M R H K L E G R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784308 368 41150 T139 V F E A L T L T R K E L D G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32347 362 41331 T137 A F K A I T M T R I K L D G E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 92.9 N.A. 92.9 89.3 N.A. N.A. 67.5 70.8 67.7 N.A. 52.5 N.A. N.A. 59.7
Protein Similarity: 100 99.7 N.A. 96.7 N.A. 95.6 94 N.A. N.A. 78.3 84.7 83.7 N.A. 67.3 N.A. N.A. 74.7
P-Site Identity: 100 100 N.A. 100 N.A. 100 93.3 N.A. N.A. 73.3 60 60 N.A. 53.3 N.A. N.A. 60
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 80 86.6 86.6 N.A. 66.6 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 67.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 100 0 0 0 0 0 0 0 0 46 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 19 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 10 0 37 0 10 % E
% Phe: 0 91 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 0 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0 % H
% Ile: 0 0 0 0 91 0 0 0 0 10 0 19 0 0 0 % I
% Lys: 0 0 19 0 0 0 0 0 0 10 37 0 0 0 37 % K
% Leu: 0 0 0 0 10 0 82 0 0 0 0 82 0 0 0 % L
% Met: 0 0 0 0 0 0 19 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 55 0 0 0 0 0 0 46 10 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 100 0 37 0 0 0 55 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 100 0 91 0 0 0 0 0 0 0 % T
% Val: 91 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _