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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UROD All Species: 33.94
Human Site: Y133 Identified Species: 74.67
UniProt: P06132 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06132 NP_000365.3 367 40787 Y133 V V A S E L G Y V F Q A I T L
Chimpanzee Pan troglodytes XP_513127 367 40740 Y133 V V A S E L G Y V F Q A I T L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532602 364 40465 Y133 A V A S E L G Y V F Q A I T L
Cat Felis silvestris
Mouse Mus musculus P70697 367 40673 Y133 A A A S E L G Y V F Q A I T L
Rat Rattus norvegicus P32362 364 40434 Y130 A V A S E L G Y V F Q A I T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422430 416 46062 Y181 D V T A E L G Y V F Q A I T L
Frog Xenopus laevis NP_001085981 367 41311 Y134 D V S E E L G Y V F R A I T L
Zebra Danio Brachydanio rerio Q9PTS2 369 41626 Y135 D V Y S E L D Y V F K A I T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V595 356 39970 Y128 G A L S R L S Y V G D A I T M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784308 368 41150 Y131 D I N Q A L S Y V F E A L T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32347 362 41331 W129 D V L K E L D W A F K A I T M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 92.9 N.A. 92.9 89.3 N.A. N.A. 67.5 70.8 67.7 N.A. 52.5 N.A. N.A. 59.7
Protein Similarity: 100 99.7 N.A. 96.7 N.A. 95.6 94 N.A. N.A. 78.3 84.7 83.7 N.A. 67.3 N.A. N.A. 74.7
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 93.3 N.A. N.A. 80 73.3 73.3 N.A. 46.6 N.A. N.A. 46.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 86.6 93.3 N.A. N.A. 86.6 86.6 80 N.A. 53.3 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 67.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 19 46 10 10 0 0 0 10 0 0 100 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 46 0 0 0 0 0 19 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 10 82 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 64 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 91 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 19 0 0 0 0 % K
% Leu: 0 0 19 0 0 100 0 0 0 0 0 0 10 0 82 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 55 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 10 64 0 0 19 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 100 0 % T
% Val: 19 73 0 0 0 0 0 0 91 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 91 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _