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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCHE
All Species:
42.42
Human Site:
S252
Identified Species:
71.79
UniProt:
P06276
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06276
NP_000046.1
602
68418
S252
F
T
R
A
I
L
Q
S
G
S
F
N
A
P
W
Chimpanzee
Pan troglodytes
XP_516857
643
72946
S293
F
T
R
A
I
L
Q
S
G
S
F
N
A
P
W
Rhesus Macaque
Macaca mulatta
P32751
141
15206
Dog
Lupus familis
XP_545267
602
68500
S252
F
T
R
A
I
L
Q
S
G
S
S
N
A
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q03311
603
68503
S253
F
T
R
A
I
L
E
S
G
S
S
N
A
P
W
Rat
Rattus norvegicus
P37136
614
68178
S260
F
H
R
A
V
L
Q
S
G
T
P
N
G
P
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
S252
F
T
R
A
I
L
Q
S
G
S
S
N
A
P
W
Chicken
Gallus gallus
P36196
767
83002
S253
F
R
R
A
V
L
Q
S
G
S
P
N
G
P
W
Frog
Xenopus laevis
NP_001121332
600
68177
S250
F
S
K
A
A
L
Q
S
G
T
P
N
T
P
W
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
S251
F
T
R
A
I
L
Q
S
G
V
P
N
T
P
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
S302
V
K
R
G
M
M
Q
S
G
T
M
N
A
P
W
Honey Bee
Apis mellifera
XP_393751
657
73886
S289
F
N
Q
A
I
M
Q
S
G
S
P
T
A
P
W
Nematode Worm
Caenorhab. elegans
P38433
620
71415
S242
F
H
R
A
I
I
Q
S
G
S
A
T
S
P
W
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
L175
V
V
S
M
N
Y
R
L
G
A
L
G
F
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
22.7
86.7
N.A.
79.2
51.6
N.A.
77.7
38.7
51.1
52
N.A.
35.7
40.4
40.8
38.7
Protein Similarity:
100
92.8
23.4
91.1
N.A.
87.5
68.2
N.A.
87.3
51.6
69.5
69.4
N.A.
52.2
57.3
57.7
52.1
P-Site Identity:
100
100
0
93.3
N.A.
86.6
66.6
N.A.
93.3
73.3
60
80
N.A.
53.3
66.6
66.6
6.6
P-Site Similarity:
100
100
0
93.3
N.A.
93.3
80
N.A.
93.3
80
80
80
N.A.
73.3
80
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
79
8
0
0
0
0
8
8
0
50
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
79
0
0
0
0
0
0
0
0
0
15
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
93
0
0
8
15
0
0
% G
% His:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
58
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
65
0
8
0
0
8
0
0
8
0
% L
% Met:
0
0
0
8
8
15
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
72
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
36
0
0
86
0
% P
% Gln:
0
0
8
0
0
0
79
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
72
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
86
0
58
22
0
8
0
0
% S
% Thr:
0
43
0
0
0
0
0
0
0
22
0
15
15
0
0
% T
% Val:
15
8
0
0
15
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
86
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _