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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCHE
All Species:
19.7
Human Site:
S492
Identified Species:
33.33
UniProt:
P06276
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06276
NP_000046.1
602
68418
S492
T
K
A
E
E
I
L
S
R
S
I
V
K
R
W
Chimpanzee
Pan troglodytes
XP_516857
643
72946
S533
T
K
A
E
E
I
L
S
R
S
I
V
K
R
W
Rhesus Macaque
Macaca mulatta
P32751
141
15206
P37
V
W
I
P
A
P
K
P
K
N
A
T
V
L
I
Dog
Lupus familis
XP_545267
602
68500
S492
T
K
A
E
E
I
L
S
R
S
I
M
K
Y
W
Cat
Felis silvestris
Mouse
Mus musculus
Q03311
603
68503
S493
T
R
A
E
E
I
F
S
R
S
I
M
K
T
W
Rat
Rattus norvegicus
P37136
614
68178
A504
T
V
E
E
R
I
F
A
Q
R
L
M
Q
Y
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
S492
T
K
A
E
E
I
L
S
R
S
I
M
R
Y
W
Chicken
Gallus gallus
P36196
767
83002
L658
Y
T
R
E
E
V
E
L
S
R
R
I
M
R
Y
Frog
Xenopus laevis
NP_001121332
600
68177
R491
P
Q
E
E
A
L
S
R
K
M
M
R
Y
W
A
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
M525
E
K
L
S
R
R
I
M
R
Y
W
A
N
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
G544
R
P
V
E
R
E
L
G
K
R
M
L
S
A
V
Honey Bee
Apis mellifera
XP_393751
657
73886
M533
E
V
N
L
S
K
K
M
M
R
Y
W
A
N
F
Nematode Worm
Caenorhab. elegans
P38433
620
71415
S495
T
D
E
E
R
E
L
S
N
R
F
M
R
Y
W
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
T404
D
A
I
A
F
Q
Y
T
E
W
L
A
P
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
22.7
86.7
N.A.
79.2
51.6
N.A.
77.7
38.7
51.1
52
N.A.
35.7
40.4
40.8
38.7
Protein Similarity:
100
92.8
23.4
91.1
N.A.
87.5
68.2
N.A.
87.3
51.6
69.5
69.4
N.A.
52.2
57.3
57.7
52.1
P-Site Identity:
100
100
0
86.6
N.A.
73.3
26.6
N.A.
80
20
6.6
13.3
N.A.
13.3
0
33.3
0
P-Site Similarity:
100
100
13.3
93.3
N.A.
86.6
60
N.A.
93.3
40
33.3
20
N.A.
33.3
6.6
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
36
8
15
0
0
8
0
0
8
15
8
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
15
0
22
72
43
15
8
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
15
0
0
0
8
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
15
0
0
43
8
0
0
0
36
8
0
0
8
% I
% Lys:
0
36
0
0
0
8
15
0
22
0
0
0
29
0
0
% K
% Leu:
0
0
8
8
0
8
43
8
0
0
15
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
15
8
8
15
36
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
8
0
0
8
8
0
% N
% Pro:
8
8
0
8
0
8
0
8
0
0
0
0
8
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
8
0
0
0
8
0
0
% Q
% Arg:
8
8
8
0
29
8
0
8
43
36
8
8
15
22
0
% R
% Ser:
0
0
0
8
8
0
8
43
8
36
0
0
8
0
0
% S
% Thr:
50
8
0
0
0
0
0
8
0
0
0
8
0
8
0
% T
% Val:
8
15
8
0
0
8
0
0
0
0
0
15
8
0
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
8
8
8
0
8
50
% W
% Tyr:
8
0
0
0
0
0
8
0
0
8
8
0
8
29
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _