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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCHE
All Species:
13.94
Human Site:
S515
Identified Species:
23.59
UniProt:
P06276
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06276
NP_000046.1
602
68418
S515
P
N
E
T
Q
N
N
S
T
S
W
P
V
F
K
Chimpanzee
Pan troglodytes
XP_516857
643
72946
S556
P
N
E
T
Q
N
N
S
T
R
W
P
V
F
K
Rhesus Macaque
Macaca mulatta
P32751
141
15206
V60
T
G
T
S
S
L
H
V
Y
D
G
K
F
L
A
Dog
Lupus familis
XP_545267
602
68500
S515
P
D
G
T
Q
N
N
S
T
R
W
P
A
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q03311
603
68503
S516
P
N
G
T
Q
G
N
S
T
M
W
P
V
F
T
Rat
Rattus norvegicus
P37136
614
68178
K527
P
N
D
P
R
D
S
K
S
P
R
W
P
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
G515
P
N
G
T
Q
S
N
G
T
R
W
P
I
F
K
Chicken
Gallus gallus
P36196
767
83002
G681
D
P
N
G
G
V
G
G
P
R
W
P
P
Y
T
Frog
Xenopus laevis
NP_001121332
600
68177
Q514
N
E
G
N
D
A
R
Q
Q
R
W
P
L
Y
T
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
R548
T
D
G
T
M
D
S
R
R
R
W
P
Q
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
W567
P
A
Q
D
G
E
E
W
P
N
F
S
K
E
D
Honey Bee
Apis mellifera
XP_393751
657
73886
Q556
G
D
V
D
V
W
T
Q
A
Y
W
P
P
H
T
Nematode Worm
Caenorhab. elegans
P38433
620
71415
S518
P
N
K
N
E
D
G
S
F
T
Q
D
V
W
P
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
L427
D
F
A
A
G
D
Y
L
F
A
C
S
T
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
22.7
86.7
N.A.
79.2
51.6
N.A.
77.7
38.7
51.1
52
N.A.
35.7
40.4
40.8
38.7
Protein Similarity:
100
92.8
23.4
91.1
N.A.
87.5
68.2
N.A.
87.3
51.6
69.5
69.4
N.A.
52.2
57.3
57.7
52.1
P-Site Identity:
100
93.3
0
66.6
N.A.
73.3
13.3
N.A.
66.6
13.3
13.3
26.6
N.A.
6.6
13.3
26.6
0
P-Site Similarity:
100
93.3
13.3
80
N.A.
73.3
46.6
N.A.
80
20
26.6
46.6
N.A.
26.6
20
60
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
0
0
8
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
15
22
8
15
8
29
0
0
0
8
0
8
0
0
15
% D
% Glu:
0
8
15
0
8
8
8
0
0
0
0
0
0
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
15
0
8
0
8
43
0
% F
% Gly:
8
8
36
8
22
8
15
15
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
8
8
0
22
% K
% Leu:
0
0
0
0
0
8
0
8
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
43
8
15
0
22
36
0
0
8
0
0
0
0
0
% N
% Pro:
58
8
0
8
0
0
0
0
15
8
0
65
22
8
8
% P
% Gln:
0
0
8
0
36
0
0
15
8
0
8
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
8
8
8
43
8
0
0
0
0
% R
% Ser:
0
0
0
8
8
8
15
36
8
8
0
15
0
0
8
% S
% Thr:
15
0
8
43
0
0
8
0
36
8
0
0
8
0
29
% T
% Val:
0
0
8
0
8
8
0
8
0
0
0
0
29
0
0
% V
% Trp:
0
0
0
0
0
8
0
8
0
0
65
8
0
8
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
8
0
0
0
22
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _