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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCHE All Species: 16.36
Human Site: S535 Identified Species: 27.69
UniProt: P06276 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06276 NP_000046.1 602 68418 S535 Y L T L N T E S T R I M T K L
Chimpanzee Pan troglodytes XP_516857 643 72946 S576 Y L T L N T E S T R I M T K L
Rhesus Macaque Macaca mulatta P32751 141 15206 R80 I V V S M N Y R V G A L G F L
Dog Lupus familis XP_545267 602 68500 S535 Y L T L N T D S P R V Y T K L
Cat Felis silvestris
Mouse Mus musculus Q03311 603 68503 K536 Y L T L N T E K S K I Y S K L
Rat Rattus norvegicus P37136 614 68178 K547 Q Y V S L N L K P L E V R R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505841 602 68511 S535 Y L T M N T D S P K I Y T K L
Chicken Gallus gallus P36196 767 83002 P701 Y A H L N A R P L S V G H G L
Frog Xenopus laevis NP_001121332 600 68177 P534 Y I A L N N R P Q Q D L Q G I
Zebra Danio Brachydanio rerio Q9DDE3 634 71980 P568 H V G L N T E P M K V H K G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07140 649 71767 E587 F S T D D K I E K L A R G P L
Honey Bee Apis mellifera XP_393751 657 73886 S576 Y M T L D T N S S E I G N G P
Nematode Worm Caenorhab. elegans P38433 620 71415 T538 S M E Y M N M T V E S S Y P S
Sea Urchin Strong. purpuratus XP_782113 508 56946 Y447 A S A N N K V Y Y Y R F L E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.8 22.7 86.7 N.A. 79.2 51.6 N.A. 77.7 38.7 51.1 52 N.A. 35.7 40.4 40.8 38.7
Protein Similarity: 100 92.8 23.4 91.1 N.A. 87.5 68.2 N.A. 87.3 51.6 69.5 69.4 N.A. 52.2 57.3 57.7 52.1
P-Site Identity: 100 100 6.6 73.3 N.A. 66.6 0 N.A. 66.6 26.6 20 33.3 N.A. 13.3 40 0 6.6
P-Site Similarity: 100 100 20 86.6 N.A. 86.6 13.3 N.A. 86.6 33.3 46.6 60 N.A. 26.6 60 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 0 0 8 0 0 0 0 15 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 15 0 15 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 29 8 0 15 8 0 0 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 8 0 15 15 29 8 % G
% His: 8 0 8 0 0 0 0 0 0 0 0 8 8 0 0 % H
% Ile: 8 8 0 0 0 0 8 0 0 0 36 0 0 0 8 % I
% Lys: 0 0 0 0 0 15 0 15 8 22 0 0 8 36 0 % K
% Leu: 0 36 0 58 8 0 8 0 8 15 0 15 8 0 65 % L
% Met: 0 15 0 8 15 0 8 0 8 0 0 15 0 0 0 % M
% Asn: 0 0 0 8 65 29 8 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 22 22 0 0 0 0 15 8 % P
% Gln: 8 0 0 0 0 0 0 0 8 8 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 15 8 0 22 8 8 8 8 8 % R
% Ser: 8 15 0 15 0 0 0 36 15 8 8 8 8 0 8 % S
% Thr: 0 0 50 0 0 50 0 8 15 0 0 0 29 0 0 % T
% Val: 0 15 15 0 0 0 8 0 15 0 22 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 58 8 0 8 0 0 8 8 8 8 0 22 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _