KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCHE
All Species:
7.88
Human Site:
Y265
Identified Species:
13.33
UniProt:
P06276
Number Species:
13
Phosphosite Substitution
Charge Score:
0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06276
NP_000046.1
602
68418
Y265
P
W
A
V
T
S
L
Y
E
A
R
N
R
T
L
Chimpanzee
Pan troglodytes
XP_516857
643
72946
Y306
P
W
A
V
T
S
L
Y
E
A
R
N
R
T
L
Rhesus Macaque
Macaca mulatta
P32751
141
15206
Dog
Lupus familis
XP_545267
602
68500
E265
P
W
A
V
M
S
L
E
E
A
R
N
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q03311
603
68503
E266
P
W
A
V
K
H
P
E
E
A
R
N
R
T
L
Rat
Rattus norvegicus
P37136
614
68178
G273
P
W
A
T
V
S
A
G
E
A
R
R
R
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
S265
P
W
A
A
V
P
P
S
E
A
K
N
R
T
L
Chicken
Gallus gallus
P36196
767
83002
A266
P
W
A
T
I
G
A
A
E
G
R
R
R
A
A
Frog
Xenopus laevis
NP_001121332
600
68177
Q263
P
W
A
T
I
T
P
Q
E
A
R
R
R
T
E
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
D264
P
W
A
T
V
T
F
D
E
A
R
R
R
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
E315
P
W
S
H
M
T
S
E
K
A
V
E
I
G
K
Honey Bee
Apis mellifera
XP_393751
657
73886
E302
P
W
A
I
I
S
R
E
E
S
I
V
R
G
I
Nematode Worm
Caenorhab. elegans
P38433
620
71415
D255
P
W
A
I
E
P
R
D
V
A
L
A
R
A
V
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
S188
L
A
M
G
Q
D
S
S
P
G
N
Q
G
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
22.7
86.7
N.A.
79.2
51.6
N.A.
77.7
38.7
51.1
52
N.A.
35.7
40.4
40.8
38.7
Protein Similarity:
100
92.8
23.4
91.1
N.A.
87.5
68.2
N.A.
87.3
51.6
69.5
69.4
N.A.
52.2
57.3
57.7
52.1
P-Site Identity:
100
100
0
86.6
N.A.
73.3
53.3
N.A.
60
40
53.3
53.3
N.A.
20
40
33.3
0
P-Site Similarity:
100
100
0
86.6
N.A.
73.3
53.3
N.A.
66.6
40
60
60
N.A.
40
60
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
79
8
0
0
15
8
0
72
0
8
0
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
15
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
29
72
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
8
0
15
0
0
8
15
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
22
0
0
0
0
0
8
0
8
0
8
% I
% Lys:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
22
0
0
0
8
0
0
8
36
% L
% Met:
0
0
8
0
15
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
36
0
0
0
% N
% Pro:
86
0
0
0
0
15
22
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
15
0
0
0
58
29
79
0
0
% R
% Ser:
0
0
8
0
0
36
15
15
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
29
15
22
0
0
0
0
0
0
0
50
15
% T
% Val:
0
0
0
29
22
0
0
0
8
0
8
8
0
0
8
% V
% Trp:
0
86
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _