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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLA
All Species:
6.06
Human Site:
S424
Identified Species:
11.11
UniProt:
P06280
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06280
NP_000160.1
429
48767
S424
L
E
N
T
M
Q
M
S
L
K
D
L
L
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093625
429
48835
S424
L
E
N
T
M
Q
M
S
I
K
D
L
L
_
_
Dog
Lupus familis
XP_538109
420
47629
T412
I
K
I
N
P
T
G
T
V
L
L
R
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P51569
419
47624
L414
V
N
P
S
G
T
V
L
F
R
L
E
R
_
_
Rat
Rattus norvegicus
Q66H12
415
46853
G407
L
Y
P
V
K
G
L
G
I
Y
T
M
M
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513605
505
56381
V498
L
G
G
F
D
A
T
V
L
F
L
P
S
K
C
Chicken
Gallus gallus
Q90744
405
45597
I391
L
C
P
K
A
L
L
I
Q
Q
Q
A
P
G
G
Frog
Xenopus laevis
NP_001089687
408
46384
Zebra Danio
Brachydanio rerio
NP_001006103
338
37828
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609354
413
47029
E406
G
V
V
M
L
K
G
E
V
Q
Y
P
V
D
L
Honey Bee
Apis mellifera
XP_001121693
462
52249
I438
C
D
L
H
L
E
D
I
F
N
T
N
E
F
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792642
415
46587
F408
V
P
P
S
G
V
T
F
V
K
I
G
T
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41947
471
52095
P458
A
I
L
N
T
T
V
P
A
H
G
I
A
F
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
81.3
N.A.
76.2
47.7
N.A.
58
48
61.3
51.5
N.A.
45.9
43.5
N.A.
46.3
Protein Similarity:
100
N.A.
99
90.2
N.A.
86
62.7
N.A.
68.7
62.9
73.8
62.9
N.A.
65.2
59.9
N.A.
64.1
P-Site Identity:
100
N.A.
92.3
6.6
N.A.
0
6.6
N.A.
13.3
6.6
0
0
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
N.A.
100
33.3
N.A.
30.7
33.3
N.A.
13.3
33.3
0
0
N.A.
33.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
0
0
8
0
0
8
8
16
8
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
8
0
8
0
0
0
16
0
0
8
0
% D
% Glu:
0
16
0
0
0
8
0
8
0
0
0
8
8
0
8
% E
% Phe:
0
0
0
8
0
0
0
8
16
8
0
0
0
16
0
% F
% Gly:
8
8
8
0
16
8
16
8
0
0
8
8
0
8
8
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
0
16
16
0
8
8
0
0
0
% I
% Lys:
0
8
0
8
8
8
0
0
0
24
0
0
0
8
0
% K
% Leu:
39
0
16
0
16
8
16
8
16
8
24
16
24
0
8
% L
% Met:
0
0
0
8
16
0
16
0
0
0
0
8
8
0
0
% M
% Asn:
0
8
16
16
0
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
8
31
0
8
0
0
8
0
0
0
16
8
0
0
% P
% Gln:
0
0
0
0
0
16
0
0
8
16
8
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% R
% Ser:
0
0
0
16
0
0
0
16
0
0
0
0
8
8
8
% S
% Thr:
0
0
0
16
8
24
16
8
0
0
16
0
8
0
0
% T
% Val:
16
8
8
8
0
8
16
8
24
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
24
% _