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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLA
All Species:
4.85
Human Site:
Y397
Identified Species:
8.89
UniProt:
P06280
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06280
NP_000160.1
429
48767
Y397
V
K
R
K
L
G
F
Y
E
W
T
S
R
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093625
429
48835
Y397
V
K
R
K
L
G
F
Y
E
W
T
S
R
L
R
Dog
Lupus familis
XP_538109
420
47629
T385
C
V
P
D
C
T
I
T
Q
L
L
P
V
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P51569
419
47624
L387
P
G
C
I
I
T
Q
L
L
P
E
K
V
H
L
Rat
Rattus norvegicus
Q66H12
415
46853
L380
T
G
D
I
I
S
G
L
H
P
E
T
N
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513605
505
56381
N471
L
P
L
S
V
L
G
N
G
L
A
C
N
P
S
Chicken
Gallus gallus
Q90744
405
45597
L364
S
G
K
I
I
S
G
L
K
T
G
D
N
F
T
Frog
Xenopus laevis
NP_001089687
408
46384
L377
N
S
C
F
I
T
R
L
L
P
S
Y
H
K
Y
Zebra Danio
Brachydanio rerio
NP_001006103
338
37828
P307
C
N
V
T
Q
I
L
P
T
Y
K
E
M
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609354
413
47029
N379
R
V
E
D
L
Y
E
N
V
D
Y
G
V
L
Y
Honey Bee
Apis mellifera
XP_001121693
462
52249
L411
E
D
V
N
Y
G
V
L
T
P
Q
T
K
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792642
415
46587
D381
V
Q
G
F
D
V
L
D
L
F
T
G
A
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41947
471
52095
G431
T
E
Q
S
Y
K
D
G
L
S
K
N
D
T
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
81.3
N.A.
76.2
47.7
N.A.
58
48
61.3
51.5
N.A.
45.9
43.5
N.A.
46.3
Protein Similarity:
100
N.A.
99
90.2
N.A.
86
62.7
N.A.
68.7
62.9
73.8
62.9
N.A.
65.2
59.9
N.A.
64.1
P-Site Identity:
100
N.A.
100
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
100
6.6
N.A.
6.6
13.3
N.A.
13.3
20
13.3
6.6
N.A.
13.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% A
% Cys:
16
0
16
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
8
16
8
0
8
8
0
8
0
8
8
0
0
% D
% Glu:
8
8
8
0
0
0
8
0
16
0
16
8
0
0
0
% E
% Phe:
0
0
0
16
0
0
16
0
0
8
0
0
0
16
0
% F
% Gly:
0
24
8
0
0
24
24
8
8
0
8
16
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% H
% Ile:
0
0
0
24
31
8
8
0
0
0
0
0
0
8
0
% I
% Lys:
0
16
8
16
0
8
0
0
8
0
16
8
8
16
8
% K
% Leu:
8
0
8
0
24
8
16
39
31
16
8
0
0
24
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
0
8
0
0
0
16
0
0
0
8
24
0
0
% N
% Pro:
8
8
8
0
0
0
0
8
0
31
0
8
0
8
0
% P
% Gln:
0
8
8
0
8
0
8
0
8
0
8
0
0
0
0
% Q
% Arg:
8
0
16
0
0
0
8
0
0
0
0
0
16
0
24
% R
% Ser:
8
8
0
16
0
16
0
0
0
8
8
16
0
0
24
% S
% Thr:
16
0
0
8
0
24
0
8
16
8
24
16
0
8
16
% T
% Val:
24
16
16
0
8
8
8
0
8
0
0
0
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
8
0
16
0
8
8
8
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _