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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCK All Species: 19.39
Human Site: S78 Identified Species: 47.41
UniProt: P06307 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06307 NP_000720.1 115 12669 S78 K A P S G R M S I V K N L Q N
Chimpanzee Pan troglodytes XP_516386 115 12637 S78 K A P S G R M S V V K N L Q N
Rhesus Macaque Macaca mulatta XP_001107333 104 11690 L68 G P Q G P P H L V A D P S K K
Dog Lupus familis XP_851915 114 12452 S77 K A P S G R M S V I K N L Q N
Cat Felis silvestris
Mouse Mus musculus P09240 115 12751 S78 K A P S G R M S V L K N L Q S
Rat Rattus norvegicus P01355 115 12822 S78 K A P S G R M S V L K N L Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518765 149 16402 F112 S D S S K I H F D H V G S V C
Chicken Gallus gallus Q9PU41 130 14072 V93 G S T G R F S V L G N R V Q S
Frog Xenopus laevis P50145 128 14182 V91 A G P S G R Y V V L P N R P I
Zebra Danio Brachydanio rerio XP_001346140 123 13292 S86 T K G S Y R R S P A A N S R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 23.4 86.9 N.A. 80.8 78.2 N.A. 35.5 50.7 48.4 45.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 36.5 91.3 N.A. 86.9 82.6 N.A. 49.6 66.9 64.8 58.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 0 86.6 N.A. 80 80 N.A. 6.6 6.6 33.3 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 93.3 N.A. 6.6 33.3 46.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 50 0 0 0 0 0 0 0 20 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 0 0 0 0 0 0 10 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 20 10 10 20 60 0 0 0 0 10 0 10 0 0 10 % G
% His: 0 0 0 0 0 0 20 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 10 10 0 0 0 0 10 % I
% Lys: 50 10 0 0 10 0 0 0 0 0 50 0 0 10 10 % K
% Leu: 0 0 0 0 0 0 0 10 10 30 0 0 50 0 0 % L
% Met: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 70 0 0 30 % N
% Pro: 0 10 60 0 10 10 0 0 10 0 10 10 0 10 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 60 0 % Q
% Arg: 0 0 0 0 10 70 10 0 0 0 0 10 10 10 0 % R
% Ser: 10 10 10 80 0 0 10 60 0 0 0 0 30 0 20 % S
% Thr: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 20 60 20 10 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _