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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 18.18
Human Site: S46 Identified Species: 80
UniProt: P06310 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06310 NULL 133 14707 S46 A S I S C R S S Q S L V Y S D
Chimpanzee Pan troglodytes XP_514960 211 22897 E113 S I S C R S S E S L L D T D D
Rhesus Macaque Macaca mulatta XP_001099063 167 18627 S46 A S I S C R S S Q S L L H S N
Dog Lupus familis XP_849967 375 40765 S188 A S I S C K A S Q S L L H S D
Cat Felis silvestris
Mouse Mus musculus P01631 113 12254 S26 A S I S C R S S Q S L V H S N
Rat Rattus norvegicus XP_002727322 172 18841 S46 A S I S C K S S Q S L V H S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.3 64 28.2 N.A. 67.6 57.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 53.5 73 32.7 N.A. 75.9 66.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 80 73.3 N.A. 86.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 84 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 17 84 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 17 0 17 67 % D
% Glu: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % H
% Ile: 0 17 84 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 17 100 34 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 84 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 17 50 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 84 17 84 0 17 84 84 17 84 0 0 0 84 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _