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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
3.94
Human Site:
Y105
Identified Species:
17.33
UniProt:
P06315
Number Species:
5
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06315
XP_001716757
115
12728
Y105
I
E
S
E
D
A
A
Y
Y
F
C
L
Q
H
D
Chimpanzee
Pan troglodytes
XP_001136986
112
12099
S104
C
L
Q
D
Y
N
Y
S
P
T
V
L
H
T
R
Rhesus Macaque
Macaca mulatta
XP_001091083
265
29016
T105
L
E
A
E
D
A
A
T
Y
Y
C
Q
Q
S
S
Dog
Lupus familis
XP_854761
146
15906
D105
L
E
A
E
D
V
R
D
Y
Y
C
Q
Q
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
P01642
115
12597
D105
V
E
S
E
D
I
A
D
Y
Y
C
Q
Q
S
N
Rat
Rattus norvegicus
XP_002726434
133
14384
I108
V
L
L
G
D
E
G
I
Y
Y
C
Q
Q
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.5
24.9
36.2
N.A.
49.5
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.8
32.4
52
N.A.
69.5
60.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
53.3
46.6
N.A.
53.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
73.3
66.6
N.A.
73.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
0
34
50
0
0
0
0
0
0
0
0
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% C
% Asp:
0
0
0
17
84
0
0
34
0
0
0
0
0
0
34
% D
% Glu:
0
67
0
67
0
17
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
17
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
17
34
0
% H
% Ile:
17
0
0
0
0
17
0
17
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
34
34
17
0
0
0
0
0
0
0
0
34
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
17
% N
% Pro:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
0
0
0
0
0
0
0
67
84
0
0
% Q
% Arg:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
17
% R
% Ser:
0
0
34
0
0
0
0
17
0
0
0
0
0
50
17
% S
% Thr:
0
0
0
0
0
0
0
17
0
17
0
0
0
17
0
% T
% Val:
34
0
0
0
0
17
0
0
0
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
17
17
84
67
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _