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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 2.12
Human Site: S108 Identified Species: 11.67
UniProt: P06326 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06326 XP_002347495 125 13579 S108 H Y S D T D D S G T S L G P W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088526 120 13121 W102 I S T V Y L Q W S S L K A S D
Dog Lupus familis XP_848736 136 15024 V120 Y Y C A R H S V R A H I L E V
Cat Felis silvestris
Mouse Mus musculus P03980 138 15558 Y121 Y C A R S D G Y Y D W F V Y W
Rat Rattus norvegicus P01805 142 16006 S125 S R G Y G G Y S E N W F V Y W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 47.2 45.5 N.A. 42.7 40.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 60 58 N.A. 59.4 55.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 0 6.6 N.A. 13.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 13.3 20 N.A. 33.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 20 0 0 0 0 0 20 0 0 20 0 0 % A
% Cys: 0 20 20 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 20 0 40 20 0 0 20 0 0 0 0 20 % D
% Glu: 0 0 0 0 0 0 0 0 20 0 0 0 0 20 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 % F
% Gly: 0 0 20 0 20 20 20 0 20 0 0 0 20 0 0 % G
% His: 20 0 0 0 0 20 0 0 0 0 20 0 0 0 0 % H
% Ile: 20 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % K
% Leu: 0 0 0 0 0 20 0 0 0 0 20 20 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % P
% Gln: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % Q
% Arg: 0 20 0 20 20 0 0 0 20 0 0 0 0 0 0 % R
% Ser: 20 20 20 0 20 0 20 40 20 20 20 0 0 20 0 % S
% Thr: 0 0 20 0 20 0 0 0 0 20 0 0 0 0 0 % T
% Val: 0 0 0 20 0 0 0 20 0 0 0 0 40 0 20 % V
% Trp: 0 0 0 0 0 0 0 20 0 0 40 0 0 0 60 % W
% Tyr: 40 40 0 20 20 0 20 20 20 0 0 0 0 40 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _