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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GSN All Species: 22.42
Human Site: S125 Identified Species: 54.81
UniProt: P06396 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06396 NP_001121136.1 782 85698 S125 N E C S Q D E S G A A A I F T
Chimpanzee Pan troglodytes XP_001161890 782 85665 S125 N E C S Q D E S G A A A I F T
Rhesus Macaque Macaca mulatta XP_001093567 784 85930 S127 N E C S Q D E S G A A A I F T
Dog Lupus familis XP_853737 781 86018 S123 K E C S Q D E S G A A A I F T
Cat Felis silvestris
Mouse Mus musculus P13020 780 85923 S123 N E C S Q D E S G A A A I F T
Rat Rattus norvegicus Q68FP1 780 86049 S123 N E C S Q D E S G A A A I F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O93510 778 85813 R121 D E S S Q D E R G A A A I F T
Frog Xenopus laevis P14885 417 46006
Zebra Danio Brachydanio rerio NP_001012312 730 81342 H100 Q Y R E V Q G H E S K A F L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07171 798 88356 A130 L E T S T D E A G A A A I L T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.7 89.2 N.A. 92.8 92.1 N.A. N.A. 76.2 38.4 66.3 N.A. 38.2 N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.2 93.3 N.A. 96.4 95.7 N.A. N.A. 86.1 45.7 77.8 N.A. 53 N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 80 0 6.6 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 86.6 0 13.3 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 80 80 90 0 0 0 % A
% Cys: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 80 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 80 0 10 0 0 80 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 70 0 % F
% Gly: 0 0 0 0 0 0 10 0 80 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 70 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 80 0 0 0 60 0 10 0 0 0 0 0 % S
% Thr: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 80 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _