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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
22.42
Human Site:
S443
Identified Species:
41.11
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
S443
Q
G
C
V
E
I
G
S
Q
R
Y
K
L
G
V
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
S590
Q
G
C
V
E
I
G
S
Q
R
Y
K
L
G
V
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
S443
Q
G
C
V
E
I
G
S
Q
R
Y
K
L
G
V
Dog
Lupus familis
XP_534118
897
103170
S412
Q
G
C
M
E
I
G
S
Q
R
Y
K
L
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
V437
Q
G
C
V
D
I
G
V
Q
R
Y
K
L
G
V
Rat
Rattus norvegicus
P33568
920
105007
A436
Q
G
C
I
D
I
G
A
Q
R
Y
K
L
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
S434
Q
G
C
I
E
I
G
S
Q
R
Y
K
L
G
V
Chicken
Gallus gallus
Q90600
921
104417
S433
Q
G
C
A
E
I
G
S
Q
R
Y
Q
L
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
E425
Q
A
V
G
Q
H
C
E
G
L
G
R
K
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
R452
E
T
T
S
D
F
G
R
K
R
L
Y
L
G
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
V296
A
A
G
D
I
N
E
V
S
F
L
T
L
D
P
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
E511
L
M
D
N
I
W
A
E
Q
R
R
L
E
A
L
Maize
Zea mays
Q3LXA7
1010
111475
E495
R
M
D
A
I
W
T
E
Q
R
K
M
E
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
93.3
86.6
N.A.
6.6
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
100
93.3
N.A.
20
N.A.
N.A.
46.6
N.A.
6.6
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
16
0
0
8
8
0
0
0
0
0
16
0
% A
% Cys:
0
0
62
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
8
24
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
0
0
0
47
0
8
24
0
0
0
0
16
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
62
8
8
0
0
70
0
8
0
8
0
0
70
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
24
62
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
8
54
8
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
8
16
8
77
0
16
% L
% Met:
0
16
0
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
70
0
0
0
8
0
0
0
77
0
0
8
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
8
0
85
8
8
0
8
0
% R
% Ser:
0
0
0
8
0
0
0
47
8
0
0
0
0
0
0
% S
% Thr:
0
8
8
0
0
0
8
0
0
0
0
8
0
0
0
% T
% Val:
0
0
8
31
0
0
0
16
0
0
0
0
0
0
62
% V
% Trp:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
62
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _