KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
32.42
Human Site:
T601
Identified Species:
59.44
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
T601
L
P
L
Q
N
N
H
T
A
A
D
M
Y
L
S
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
T748
L
P
L
Q
N
N
H
T
A
A
D
M
Y
L
S
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
T601
L
P
L
Q
N
N
H
T
A
A
D
M
Y
L
S
Dog
Lupus familis
XP_534118
897
103170
T570
L
P
L
Q
S
N
H
T
A
A
D
M
Y
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
T594
L
P
L
Q
G
N
H
T
A
A
D
M
Y
L
S
Rat
Rattus norvegicus
P33568
920
105007
T593
L
P
L
Q
S
N
H
T
A
A
D
M
Y
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
T590
L
P
L
Q
H
S
H
T
A
A
D
L
Y
L
S
Chicken
Gallus gallus
Q90600
921
104417
T593
L
P
L
Q
H
N
H
T
A
A
D
L
Y
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
Q580
R
E
E
G
P
G
E
Q
A
E
P
P
A
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
I671
L
P
S
K
V
L
T
I
D
S
N
S
R
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
V451
L
A
C
A
L
E
V
V
M
V
T
F
G
Y
T
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
S710
S
V
L
V
E
R
N
S
F
T
S
P
V
K
D
Maize
Zea mays
Q3LXA7
1010
111475
N683
R
A
C
T
E
R
R
N
V
L
V
D
S
N
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
86.6
N.A.
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
100
100
N.A.
6.6
N.A.
N.A.
40
N.A.
13.3
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
0
0
0
0
70
62
0
0
8
0
0
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
62
8
0
0
8
% D
% Glu:
0
8
8
0
16
8
8
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
8
8
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
16
0
62
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
77
0
70
0
8
8
0
0
0
8
0
16
0
62
16
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
47
0
0
0
% M
% Asn:
0
0
0
0
24
54
8
8
0
0
8
0
0
8
0
% N
% Pro:
0
70
0
0
8
0
0
0
0
0
8
16
0
0
0
% P
% Gln:
0
0
0
62
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
0
0
16
8
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
8
0
16
8
0
8
0
8
8
8
8
0
70
% S
% Thr:
0
0
0
8
0
0
8
62
0
8
8
0
0
8
8
% T
% Val:
0
8
0
8
8
0
8
8
8
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
62
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _