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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
26.06
Human Site:
Y239
Identified Species:
47.78
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
Y239
P
M
L
L
K
E
P
Y
K
T
A
V
I
P
I
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
Y386
P
V
L
L
K
E
P
Y
K
T
A
V
I
P
I
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
Y239
P
V
L
L
K
E
P
Y
K
T
A
V
I
P
I
Dog
Lupus familis
XP_534118
897
103170
P214
P
Y
K
T
A
V
I
P
F
N
G
S
P
R
T
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
Y233
P
A
L
L
R
E
P
Y
K
T
A
A
I
P
I
Rat
Rattus norvegicus
P33568
920
105007
Y232
P
A
L
L
R
E
P
Y
K
T
A
A
T
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
Y224
P
A
V
L
K
E
P
Y
R
N
A
V
T
A
I
Chicken
Gallus gallus
Q90600
921
104417
Y227
P
A
M
L
K
E
P
Y
K
S
A
V
T
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
Y225
P
S
L
L
Q
S
P
Y
N
S
V
V
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
P223
D
L
L
N
P
N
F
P
G
L
P
S
N
F
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
E104
E
H
M
G
K
V
E
E
I
F
S
F
S
D
T
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
V266
F
N
D
S
Q
W
F
V
R
K
G
D
K
G
V
Maize
Zea mays
Q3LXA7
1010
111475
G249
I
K
D
S
S
Y
F
G
K
K
S
D
R
G
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
93.3
93.3
6.6
N.A.
80
73.3
N.A.
60
60
N.A.
40
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
86.6
80
N.A.
73.3
80
N.A.
53.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
0
8
0
0
0
0
0
54
16
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
0
0
0
0
0
0
0
16
0
8
0
% D
% Glu:
8
0
0
0
0
54
8
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
24
0
8
8
0
8
0
8
0
% F
% Gly:
0
0
0
8
0
0
0
8
8
0
16
0
0
16
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
8
0
0
0
31
0
47
% I
% Lys:
0
8
8
0
47
0
0
0
54
16
0
0
8
0
0
% K
% Leu:
0
8
54
62
0
0
0
0
0
8
0
0
0
0
8
% L
% Met:
0
8
16
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
8
0
0
8
16
0
0
8
0
8
% N
% Pro:
70
0
0
0
8
0
62
16
0
0
8
0
8
39
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
16
0
0
0
16
0
0
0
8
8
0
% R
% Ser:
0
8
0
16
8
8
0
0
0
16
16
16
16
8
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
39
0
0
24
0
16
% T
% Val:
0
16
8
0
0
16
0
8
0
0
8
47
0
0
16
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _