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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGR
All Species:
4.55
Human Site:
S450
Identified Species:
12.5
UniProt:
P06401
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06401
NP_000917.3
933
98981
S450
P
A
S
A
S
V
S
S
A
S
S
S
G
S
T
Chimpanzee
Pan troglodytes
A7X8B3
933
98902
S450
P
A
S
A
S
V
S
S
A
S
S
S
G
S
T
Rhesus Macaque
Macaca mulatta
Q6QT55
895
96519
L421
A
S
S
S
W
H
T
L
F
T
A
E
E
G
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q00175
923
99056
P445
P
S
S
A
A
V
S
P
A
S
S
S
G
S
A
Rat
Rattus norvegicus
Q63449
923
99389
P444
A
P
S
A
A
V
S
P
V
S
S
S
G
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510439
499
56093
A95
G
T
G
Q
G
E
G
A
R
K
R
E
D
W
N
Chicken
Gallus gallus
P07812
786
85725
A382
Q
A
L
G
F
P
A
A
V
L
K
E
G
L
P
Frog
Xenopus laevis
NP_001079100
732
82004
K328
T
F
Q
P
T
S
M
K
E
T
Y
L
S
E
I
Zebra Danio
Brachydanio rerio
XP_001923769
617
69335
P213
W
M
S
A
A
D
S
P
F
W
Y
Q
S
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
32.6
N.A.
N.A.
80.4
81.2
N.A.
45.7
56.2
47
36.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
46.8
N.A.
N.A.
85.2
85.8
N.A.
50.2
65.9
58.5
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
N.A.
N.A.
73.3
60
N.A.
0
13.3
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
N.A.
N.A.
86.6
66.6
N.A.
6.6
26.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
34
0
56
34
0
12
23
34
0
12
0
0
12
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
12
0
0
34
12
12
0
% E
% Phe:
0
12
0
0
12
0
0
0
23
0
0
0
0
0
0
% F
% Gly:
12
0
12
12
12
0
12
0
0
0
0
0
56
12
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
12
0
12
12
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
12
0
12
0
12
0
12
0
% L
% Met:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% N
% Pro:
34
12
0
12
0
12
0
34
0
0
0
0
0
0
12
% P
% Gln:
12
0
12
12
0
0
0
0
0
0
0
12
0
0
12
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% R
% Ser:
0
23
67
12
23
12
56
23
0
45
45
45
23
45
0
% S
% Thr:
12
12
0
0
12
0
12
0
0
23
0
0
0
0
23
% T
% Val:
0
0
0
0
0
45
0
0
23
0
0
0
0
0
0
% V
% Trp:
12
0
0
0
12
0
0
0
0
12
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _