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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP5B All Species: 14.55
Human Site: S25 Identified Species: 20
UniProt: P06576 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06576 NP_001677.2 529 56560 S25 R R L T P S A S L P P A Q L L
Chimpanzee Pan troglodytes XP_509149 529 56426 S25 R G L T P S A S L P P A Q L L
Rhesus Macaque Macaca mulatta XP_001091520 529 56381 S25 R G L T P S A S L P P A Q L L
Dog Lupus familis XP_531639 527 56267 P24 L R G L G P S P L P Q V K V L
Cat Felis silvestris
Mouse Mus musculus P56480 529 56282 A25 R G L S P S A A L P Q A Q L L
Rat Rattus norvegicus P10719 529 56335 A25 R G L N P L A A L P Q A H L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLC5 533 56609 F30 A A G P S H G F L P L L L S R
Frog Xenopus laevis NP_001080126 525 56355 P22 A L K P T S S P V Q L G Q N L
Zebra Danio Brachydanio rerio NP_001019600 517 54982 H21 Q A L K P G V H P L K A L N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q05825 505 54089 G19 K N L L P F L G Q L S R S H A
Honey Bee Apis mellifera XP_624156 516 55112 S19 A L R A V K P S I L Q N E I T
Nematode Worm Caenorhab. elegans P46561 538 57508 S34 P A A S I R L S S N N V E S K
Sea Urchin Strong. purpuratus NP_001116974 523 55956 L24 K S Q F S H S L S Q Q T S K T
Poplar Tree Populus trichocarpa
Maize Zea mays P19023 553 59085 A24 L R A A S P A A P R P R A P P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5A9 559 59841 S23 S R S T S K S S L I G S R N P
Baker's Yeast Sacchar. cerevisiae P00830 511 54775 S26 K Q S A P L L S T S W K R C M
Red Bread Mold Neurospora crassa P23704 519 55515 L30 R A V R P A A L N L R A P A L
Conservation
Percent
Protein Identity: 100 99.2 98.3 96 N.A. 96.2 95.6 N.A. N.A. 91.9 90.5 88.6 N.A. 84.1 85.2 79.1 80.3
Protein Similarity: 100 99.2 98.4 97.1 N.A. 97.7 97.1 N.A. N.A. 94.5 93.7 92.2 N.A. 89 91.1 84.9 86.3
P-Site Identity: 100 93.3 93.3 26.6 N.A. 73.3 60 N.A. N.A. 13.3 20 20 N.A. 13.3 6.6 6.6 0
P-Site Similarity: 100 93.3 93.3 46.6 N.A. 86.6 66.6 N.A. N.A. 13.3 33.3 26.6 N.A. 20 26.6 20 13.3
Percent
Protein Identity: N.A. 72.8 N.A. 70.3 72.7 74.4
Protein Similarity: N.A. 80.6 N.A. 80.3 82.8 82
P-Site Identity: N.A. 20 N.A. 26.6 13.3 33.3
P-Site Similarity: N.A. 26.6 N.A. 46.6 40 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 24 12 18 0 6 42 18 0 0 0 42 6 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 6 0 6 0 6 0 0 0 0 0 0 0 % F
% Gly: 0 24 12 0 6 6 6 6 0 0 6 6 0 0 6 % G
% His: 0 0 0 0 0 12 0 6 0 0 0 0 6 6 0 % H
% Ile: 0 0 0 0 6 0 0 0 6 6 0 0 0 6 0 % I
% Lys: 18 0 6 6 0 12 0 0 0 0 6 6 6 6 6 % K
% Leu: 12 12 42 12 0 12 18 12 48 24 12 6 12 30 48 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % M
% Asn: 0 6 0 6 0 0 0 0 6 6 6 6 0 18 0 % N
% Pro: 6 0 0 12 53 12 6 12 12 42 24 0 6 6 12 % P
% Gln: 6 6 6 0 0 0 0 0 6 12 30 0 30 0 0 % Q
% Arg: 36 24 6 6 0 6 0 0 0 6 6 12 12 0 6 % R
% Ser: 6 6 12 12 24 30 24 42 12 6 6 6 12 12 0 % S
% Thr: 0 0 0 24 6 0 0 0 6 0 0 6 0 0 12 % T
% Val: 0 0 6 0 6 0 6 0 6 0 0 12 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _