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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP5B All Species: 31.21
Human Site: S51 Identified Species: 42.92
UniProt: P06576 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06576 NP_001677.2 529 56560 S51 R D Y A A Q T S P S P K A G A
Chimpanzee Pan troglodytes XP_509149 529 56426 S51 R D Y A A Q T S P S P K A G A
Rhesus Macaque Macaca mulatta XP_001091520 529 56381 S51 R D Y A A Q T S P S P K A G A
Dog Lupus familis XP_531639 527 56267 S50 R D Y A T Q T S P S P K A G A
Cat Felis silvestris
Mouse Mus musculus P56480 529 56282 S51 R D Y A A Q A S A A P K A G T
Rat Rattus norvegicus P10719 529 56335 S51 R D Y A A Q S S A A P K A G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLC5 533 56609 A56 R D H A A Q A A P A A K A G S
Frog Xenopus laevis NP_001080126 525 56355 S48 R D Y A A Q T S A A A K P G T
Zebra Danio Brachydanio rerio NP_001019600 517 54982 A47 A P A A A A A A A S G R I V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q05825 505 54089 G45 G K I V A V I G A V V D V Q F
Honey Bee Apis mellifera XP_624156 516 55112 S45 D Y A K A A S S K G G A Q G K
Nematode Worm Caenorhab. elegans P46561 538 57508 S60 A A A A T K V S A K A T A A N
Sea Urchin Strong. purpuratus NP_001116974 523 55956 S50 Y A A E A K T S A S P V S G Q
Poplar Tree Populus trichocarpa
Maize Zea mays P19023 553 59085 S50 R A A A Y A S S A A A Q A A P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5A9 559 59841 G49 A P C G T L L G R V A E Y S T
Baker's Yeast Sacchar. cerevisiae P00830 511 54775 A52 K V T A V I G A I V D V H F E
Red Bread Mold Neurospora crassa P23704 519 55515 G56 G K I Y Q V I G A V V D V K F
Conservation
Percent
Protein Identity: 100 99.2 98.3 96 N.A. 96.2 95.6 N.A. N.A. 91.9 90.5 88.6 N.A. 84.1 85.2 79.1 80.3
Protein Similarity: 100 99.2 98.4 97.1 N.A. 97.7 97.1 N.A. N.A. 94.5 93.7 92.2 N.A. 89 91.1 84.9 86.3
P-Site Identity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. N.A. 60 66.6 26.6 N.A. 6.6 20 20 40
P-Site Similarity: 100 100 100 93.3 N.A. 80 86.6 N.A. N.A. 86.6 73.3 40 N.A. 6.6 26.6 26.6 53.3
Percent
Protein Identity: N.A. 72.8 N.A. 70.3 72.7 74.4
Protein Similarity: N.A. 80.6 N.A. 80.3 82.8 82
P-Site Identity: N.A. 26.6 N.A. 0 6.6 0
P-Site Similarity: N.A. 46.6 N.A. 6.6 20 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 18 30 71 65 18 18 18 53 30 30 6 53 12 30 % A
% Cys: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 48 0 0 0 0 0 0 0 0 6 12 0 0 0 % D
% Glu: 0 0 0 6 0 0 0 0 0 0 0 6 0 0 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 12 % F
% Gly: 12 0 0 6 0 0 6 18 0 6 12 0 0 59 0 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 0 6 0 0 % H
% Ile: 0 0 12 0 0 6 12 0 6 0 0 0 6 0 0 % I
% Lys: 6 12 0 6 0 12 0 0 6 6 0 48 0 6 6 % K
% Leu: 0 0 0 0 0 6 6 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % N
% Pro: 0 12 0 0 0 0 0 0 30 0 42 0 6 0 6 % P
% Gln: 0 0 0 0 6 48 0 0 0 0 0 6 6 6 6 % Q
% Arg: 53 0 0 0 0 0 0 0 6 0 0 6 0 0 0 % R
% Ser: 0 0 0 0 0 0 18 65 0 36 0 0 6 6 6 % S
% Thr: 0 0 6 0 18 0 36 0 0 0 0 6 0 0 24 % T
% Val: 0 6 0 6 6 12 6 0 0 24 12 12 12 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 6 42 6 6 0 0 0 0 0 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _