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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP5B All Species: 15.45
Human Site: T21 Identified Species: 21.25
UniProt: P06576 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06576 NP_001677.2 529 56560 T21 S G A L R R L T P S A S L P P
Chimpanzee Pan troglodytes XP_509149 529 56426 T21 S G A L R G L T P S A S L P P
Rhesus Macaque Macaca mulatta XP_001091520 529 56381 T21 S G A L R G L T P S A S L P P
Dog Lupus familis XP_531639 527 56267 L20 A S G A L R G L G P S P L P Q
Cat Felis silvestris
Mouse Mus musculus P56480 529 56282 S21 S G A L R G L S P S A A L P Q
Rat Rattus norvegicus P10719 529 56335 N21 S G A L R G L N P L A A L P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLC5 533 56609 P26 A L R R A A G P S H G F L P L
Frog Xenopus laevis NP_001080126 525 56355 P18 G A L R A L K P T S S P V Q L
Zebra Danio Brachydanio rerio NP_001019600 517 54982 K17 T G A L Q A L K P G V H P L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q05825 505 54089 L15 S K A D K N L L P F L G Q L S
Honey Bee Apis mellifera XP_624156 516 55112 A15 A A A G A L R A V K P S I L Q
Nematode Worm Caenorhab. elegans P46561 538 57508 S30 K C A L P A A S I R L S S N N
Sea Urchin Strong. purpuratus NP_001116974 523 55956 F20 V R A A K S Q F S H S L S Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays P19023 553 59085 A20 S A S R L R A A S P A A P R P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5A9 559 59841 T19 R S S S S R S T S K S S L I G
Baker's Yeast Sacchar. cerevisiae P00830 511 54775 A22 F K A A K Q S A P L L S T S W
Red Bread Mold Neurospora crassa P23704 519 55515 R26 A A S R R A V R P A A L N L R
Conservation
Percent
Protein Identity: 100 99.2 98.3 96 N.A. 96.2 95.6 N.A. N.A. 91.9 90.5 88.6 N.A. 84.1 85.2 79.1 80.3
Protein Similarity: 100 99.2 98.4 97.1 N.A. 97.7 97.1 N.A. N.A. 94.5 93.7 92.2 N.A. 89 91.1 84.9 86.3
P-Site Identity: 100 93.3 93.3 20 N.A. 73.3 66.6 N.A. N.A. 13.3 6.6 33.3 N.A. 26.6 13.3 20 6.6
P-Site Similarity: 100 93.3 93.3 33.3 N.A. 86.6 73.3 N.A. N.A. 20 20 46.6 N.A. 33.3 26.6 26.6 20
Percent
Protein Identity: N.A. 72.8 N.A. 70.3 72.7 74.4
Protein Similarity: N.A. 80.6 N.A. 80.3 82.8 82
P-Site Identity: N.A. 26.6 N.A. 26.6 20 20
P-Site Similarity: N.A. 40 N.A. 40 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 24 65 18 18 24 12 18 0 6 42 18 0 0 0 % A
% Cys: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 6 0 0 0 0 0 0 6 0 6 0 6 0 0 0 % F
% Gly: 6 36 6 6 0 24 12 0 6 6 6 6 0 0 6 % G
% His: 0 0 0 0 0 0 0 0 0 12 0 6 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 6 0 0 0 6 6 0 % I
% Lys: 6 12 0 0 18 0 6 6 0 12 0 0 0 0 6 % K
% Leu: 0 6 6 42 12 12 42 12 0 12 18 12 48 24 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 6 0 6 0 0 0 0 6 6 6 % N
% Pro: 0 0 0 0 6 0 0 12 53 12 6 12 12 42 24 % P
% Gln: 0 0 0 0 6 6 6 0 0 0 0 0 6 12 30 % Q
% Arg: 6 6 6 24 36 24 6 6 0 6 0 0 0 6 6 % R
% Ser: 42 12 18 6 6 6 12 12 24 30 24 42 12 6 6 % S
% Thr: 6 0 0 0 0 0 0 24 6 0 0 0 6 0 0 % T
% Val: 6 0 0 0 0 0 6 0 6 0 6 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _