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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP5B All Species: 54.24
Human Site: Y269 Identified Species: 74.58
UniProt: P06576 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06576 NP_001677.2 529 56560 Y269 T S K V A L V Y G Q M N E P P
Chimpanzee Pan troglodytes XP_509149 529 56426 Y269 T S K V A L V Y G Q M N E P P
Rhesus Macaque Macaca mulatta XP_001091520 529 56381 Y269 T S K V A L V Y G Q M N E P P
Dog Lupus familis XP_531639 527 56267 Y268 T S K V A L V Y G Q M N E P P
Cat Felis silvestris
Mouse Mus musculus P56480 529 56282 Y269 T S K V A L V Y G Q M N E P P
Rat Rattus norvegicus P10719 529 56335 Y269 T S K V A L V Y G Q M N E P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLC5 533 56609 Y274 T S K V A L V Y G Q M N E P P
Frog Xenopus laevis NP_001080126 525 56355 Y266 T S K V A L V Y G Q M N E P P
Zebra Danio Brachydanio rerio NP_001019600 517 54982 Y258 T S K V A L V Y G Q M N E P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q05825 505 54089 Y246 T S K V A L V Y G Q M N E P P
Honey Bee Apis mellifera XP_624156 516 55112 Y259 T S K V A L V Y G Q M N E P P
Nematode Worm Caenorhab. elegans P46561 538 57508 Y278 N S K V S L V Y G Q M N E P P
Sea Urchin Strong. purpuratus NP_001116974 523 55956 Y264 T S K V A L V Y G Q M N E P P
Poplar Tree Populus trichocarpa
Maize Zea mays P19023 553 59085 L291 Q S E S K C A L V Y G Q M N E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5A9 559 59841 L297 Q S E S K C A L V Y G Q M N E
Baker's Yeast Sacchar. cerevisiae P00830 511 54775 G253 S K V A L V F G Q M N E P P G
Red Bread Mold Neurospora crassa P23704 519 55515 G258 S K V A L V F G Q M N E P P G
Conservation
Percent
Protein Identity: 100 99.2 98.3 96 N.A. 96.2 95.6 N.A. N.A. 91.9 90.5 88.6 N.A. 84.1 85.2 79.1 80.3
Protein Similarity: 100 99.2 98.4 97.1 N.A. 97.7 97.1 N.A. N.A. 94.5 93.7 92.2 N.A. 89 91.1 84.9 86.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 100 86.6 100
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 100 93.3 100
Percent
Protein Identity: N.A. 72.8 N.A. 70.3 72.7 74.4
Protein Similarity: N.A. 80.6 N.A. 80.3 82.8 82
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. 13.3 N.A. 13.3 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 71 0 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 12 0 0 0 0 0 0 0 0 12 77 0 12 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 12 77 0 12 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 77 0 12 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 12 77 0 12 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 12 77 0 12 0 0 % M
% Asn: 6 0 0 0 0 0 0 0 0 0 12 77 0 12 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 12 89 77 % P
% Gln: 12 0 0 0 0 0 0 0 12 77 0 12 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 89 0 12 6 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 12 77 0 12 77 0 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 77 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _