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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5B
All Species:
23.94
Human Site:
Y46
Identified Species:
32.92
UniProt:
P06576
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06576
NP_001677.2
529
56560
Y46
A
V
H
P
V
R
D
Y
A
A
Q
T
S
P
S
Chimpanzee
Pan troglodytes
XP_509149
529
56426
Y46
A
V
H
P
V
R
D
Y
A
A
Q
T
S
P
S
Rhesus Macaque
Macaca mulatta
XP_001091520
529
56381
Y46
A
V
H
P
V
R
D
Y
A
A
Q
T
S
P
S
Dog
Lupus familis
XP_531639
527
56267
Y45
A
L
Q
S
A
R
D
Y
A
T
Q
T
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P56480
529
56282
Y46
G
V
H
P
A
R
D
Y
A
A
Q
A
S
A
A
Rat
Rattus norvegicus
P10719
529
56335
Y46
G
V
H
P
A
R
D
Y
A
A
Q
S
S
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLC5
533
56609
H51
A
V
G
A
R
R
D
H
A
A
Q
A
A
P
A
Frog
Xenopus laevis
NP_001080126
525
56355
Y43
A
L
H
S
R
R
D
Y
A
A
Q
T
S
A
A
Zebra Danio
Brachydanio rerio
NP_001019600
517
54982
A42
R
R
G
Y
A
A
P
A
A
A
A
A
A
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q05825
505
54089
I40
A
A
A
A
N
G
K
I
V
A
V
I
G
A
V
Honey Bee
Apis mellifera
XP_624156
516
55112
A40
S
V
N
S
R
D
Y
A
K
A
A
S
S
K
G
Nematode Worm
Caenorhab. elegans
P46561
538
57508
A55
V
A
T
Q
Q
A
A
A
A
T
K
V
S
A
K
Sea Urchin
Strong. purpuratus
NP_001116974
523
55956
A45
C
S
K
R
S
Y
A
A
E
A
K
T
S
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P19023
553
59085
A45
G
Y
L
F
N
R
A
A
A
Y
A
S
S
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5A9
559
59841
C44
P
A
H
G
A
A
P
C
G
T
L
L
G
R
V
Baker's Yeast
Sacchar. cerevisiae
P00830
511
54775
T47
T
P
I
T
G
K
V
T
A
V
I
G
A
I
V
Red Bread Mold
Neurospora crassa
P23704
519
55515
I51
A
G
V
G
D
G
K
I
Y
Q
V
I
G
A
V
Conservation
Percent
Protein Identity:
100
99.2
98.3
96
N.A.
96.2
95.6
N.A.
N.A.
91.9
90.5
88.6
N.A.
84.1
85.2
79.1
80.3
Protein Similarity:
100
99.2
98.4
97.1
N.A.
97.7
97.1
N.A.
N.A.
94.5
93.7
92.2
N.A.
89
91.1
84.9
86.3
P-Site Identity:
100
100
100
66.6
N.A.
66.6
66.6
N.A.
N.A.
53.3
66.6
20
N.A.
13.3
20
13.3
26.6
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
80
N.A.
N.A.
73.3
80
26.6
N.A.
13.3
40
20
33.3
Percent
Protein Identity:
N.A.
72.8
N.A.
70.3
72.7
74.4
Protein Similarity:
N.A.
80.6
N.A.
80.3
82.8
82
P-Site Identity:
N.A.
20
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
33.3
N.A.
6.6
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
48
18
6
12
30
18
18
30
71
65
18
18
18
53
30
% A
% Cys:
6
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
6
6
48
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% E
% Phe:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
18
6
12
12
6
12
0
0
6
0
0
6
18
0
6
% G
% His:
0
0
42
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
0
0
0
12
0
0
6
12
0
6
0
% I
% Lys:
0
0
6
0
0
6
12
0
6
0
12
0
0
6
6
% K
% Leu:
0
12
6
0
0
0
0
0
0
0
6
6
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
6
6
0
30
0
0
12
0
0
0
0
0
0
30
0
% P
% Gln:
0
0
6
6
6
0
0
0
0
6
48
0
0
0
0
% Q
% Arg:
6
6
0
6
18
53
0
0
0
0
0
0
0
6
0
% R
% Ser:
6
6
0
18
6
0
0
0
0
0
0
18
65
0
36
% S
% Thr:
6
0
6
6
0
0
0
6
0
18
0
36
0
0
0
% T
% Val:
6
42
6
0
18
0
6
0
6
6
12
6
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
6
0
6
6
42
6
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _