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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5B
All Species:
66.36
Human Site:
Y508
Identified Species:
91.25
UniProt:
P06576
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06576
NP_001677.2
529
56560
Y508
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Chimpanzee
Pan troglodytes
XP_509149
529
56426
Y508
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Rhesus Macaque
Macaca mulatta
XP_001091520
529
56381
Y508
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Dog
Lupus familis
XP_531639
527
56267
Y507
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P56480
529
56282
Y508
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Rat
Rattus norvegicus
P10719
529
56335
Y508
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLC5
533
56609
Y513
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Frog
Xenopus laevis
NP_001080126
525
56355
Y505
N
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Zebra Danio
Brachydanio rerio
NP_001019600
517
54982
Y497
A
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q05825
505
54089
Y485
H
L
P
E
V
A
F
Y
M
V
G
P
I
E
E
Honey Bee
Apis mellifera
XP_624156
516
55112
Y498
H
L
P
E
V
A
F
Y
M
V
G
P
I
E
E
Nematode Worm
Caenorhab. elegans
P46561
538
57508
Y517
H
L
P
E
V
A
F
Y
M
Q
G
G
I
D
D
Sea Urchin
Strong. purpuratus
NP_001116974
523
55956
Y503
H
L
P
E
I
A
F
Y
M
V
G
N
I
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P19023
553
59085
Y532
D
L
P
E
Q
S
F
Y
M
V
G
G
I
E
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5A9
559
59841
Y538
D
L
S
E
Q
S
F
Y
M
V
G
G
I
D
E
Baker's Yeast
Sacchar. cerevisiae
P00830
511
54775
Y491
N
I
P
E
H
A
F
Y
M
V
G
G
I
E
D
Red Bread Mold
Neurospora crassa
P23704
519
55515
Y496
D
L
P
E
G
A
F
Y
M
V
G
D
F
A
S
Conservation
Percent
Protein Identity:
100
99.2
98.3
96
N.A.
96.2
95.6
N.A.
N.A.
91.9
90.5
88.6
N.A.
84.1
85.2
79.1
80.3
Protein Similarity:
100
99.2
98.4
97.1
N.A.
97.7
97.1
N.A.
N.A.
94.5
93.7
92.2
N.A.
89
91.1
84.9
86.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
93.3
93.3
66.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
93.3
93.3
80
86.6
Percent
Protein Identity:
N.A.
72.8
N.A.
70.3
72.7
74.4
Protein Similarity:
N.A.
80.6
N.A.
80.3
82.8
82
P-Site Identity:
N.A.
80
N.A.
66.6
66.6
60
P-Site Similarity:
N.A.
86.6
N.A.
80
86.6
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
89
0
0
0
0
0
0
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
18
0
0
0
0
0
0
0
0
0
0
6
0
12
18
% D
% Glu:
0
0
0
100
0
0
0
0
0
0
0
0
0
77
77
% E
% Phe:
0
0
0
0
0
0
100
0
0
0
0
0
6
0
0
% F
% Gly:
0
0
0
0
6
0
0
0
0
0
100
24
0
0
0
% G
% His:
65
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
0
6
0
0
0
0
0
0
0
95
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
95
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% N
% Pro:
0
0
95
0
0
0
0
0
0
0
0
65
0
0
0
% P
% Gln:
0
0
0
0
65
0
0
0
0
6
0
0
0
6
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
6
0
0
12
0
0
0
0
0
0
0
0
6
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
18
0
0
0
0
95
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _