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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C2
All Species:
17.27
Human Site:
S488
Identified Species:
54.29
UniProt:
P06681
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06681
NP_000054.2
752
83268
S488
H
V
T
I
K
P
K
S
Q
E
T
C
R
G
A
Chimpanzee
Pan troglodytes
Q8SQ74
752
83261
S488
H
V
T
I
K
P
K
S
Q
E
T
C
R
G
A
Rhesus Macaque
Macaca mulatta
XP_001113626
752
83270
S488
H
V
T
I
K
P
K
S
Q
E
T
C
R
G
A
Dog
Lupus familis
XP_860410
748
82729
S487
H
V
I
I
K
P
R
S
Q
E
T
C
R
G
A
Cat
Felis silvestris
Mouse
Mus musculus
P21180
760
84708
S495
Q
V
T
F
K
P
K
S
K
E
T
C
Q
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518715
697
76676
V464
E
D
T
A
L
W
R
V
T
V
G
D
P
G
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001116166
662
74894
E430
P
S
D
A
Y
D
F
E
I
G
G
Q
N
Y
K
Zebra Danio
Brachydanio rerio
NP_571413
737
82909
Q494
Q
L
S
I
A
Q
S
Q
I
S
D
C
M
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.7
84.3
N.A.
75.2
N.A.
N.A.
50
N.A.
35.9
34.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.6
90.8
N.A.
84.8
N.A.
N.A.
63.9
N.A.
54.6
53.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
66.6
N.A.
N.A.
13.3
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
20
N.A.
0
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
13
0
0
0
0
0
0
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% C
% Asp:
0
13
13
0
0
13
0
0
0
0
13
13
0
0
0
% D
% Glu:
13
0
0
0
0
0
0
13
0
63
0
0
0
0
0
% E
% Phe:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
13
25
0
0
88
0
% G
% His:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
63
0
0
0
0
25
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
63
0
50
0
13
0
0
0
0
0
13
% K
% Leu:
0
13
0
0
13
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% N
% Pro:
13
0
0
0
0
63
0
0
0
0
0
0
13
0
13
% P
% Gln:
25
0
0
0
0
13
0
13
50
0
0
13
13
0
0
% Q
% Arg:
0
0
0
0
0
0
25
0
0
0
0
0
50
0
0
% R
% Ser:
0
13
13
0
0
0
13
63
0
13
0
0
0
0
25
% S
% Thr:
0
0
63
0
0
0
0
0
13
0
63
0
0
0
0
% T
% Val:
0
63
0
0
0
0
0
13
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _