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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APOA4
All Species:
7.58
Human Site:
S259
Identified Species:
16.67
UniProt:
P06727
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06727
NP_000473
396
45399
S259
L
K
A
R
I
S
A
S
A
E
E
L
R
Q
R
Chimpanzee
Pan troglodytes
Q9GJU3
317
36083
R224
A
G
Q
P
L
Q
E
R
A
Q
A
W
G
E
R
Rhesus Macaque
Macaca mulatta
XP_001090730
572
65150
S390
L
K
A
R
I
S
A
S
A
E
E
L
R
Q
R
Dog
Lupus familis
XP_546510
407
46257
N282
L
K
A
K
I
S
A
N
A
E
E
L
R
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
P06728
395
45011
K259
L
Q
T
K
V
S
A
K
I
D
Q
L
Q
K
N
Rat
Rattus norvegicus
P02651
391
44438
N259
L
Q
T
K
V
S
T
N
I
D
Q
L
Q
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517327
362
41011
Y247
L
R
V
R
L
G
P
Y
A
E
E
M
Q
A
R
Chicken
Gallus gallus
P08250
264
30662
A171
L
T
P
V
A
E
E
A
R
D
R
L
R
G
H
Frog
Xenopus laevis
NP_001088004
369
42412
F259
V
D
T
Q
I
R
E
F
T
E
Q
L
K
D
Q
Zebra Danio
Brachydanio rerio
O42363
262
30238
R169
E
P
L
M
D
D
I
R
K
A
F
E
S
N
I
Tiger Blowfish
Takifugu rubipres
NP_001027893
255
28474
E162
T
L
M
Q
K
S
E
E
L
K
S
S
L
E
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.2
64.6
77.8
N.A.
62.1
62.6
N.A.
36.1
23.2
38.3
22.9
23.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.9
66.7
85
N.A.
79.2
79.8
N.A.
57.3
45.2
63.1
40.4
41.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
26.6
20
N.A.
40
20
20
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
73.3
73.3
N.A.
66.6
33.3
53.3
0
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
28
0
10
0
37
10
46
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
10
0
0
0
28
0
0
0
10
0
% D
% Glu:
10
0
0
0
0
10
37
10
0
46
37
10
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
37
0
10
0
19
0
0
0
0
0
10
% I
% Lys:
0
28
0
28
10
0
0
10
10
10
0
0
10
19
0
% K
% Leu:
64
10
10
0
19
0
0
0
10
0
0
64
10
0
0
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
0
0
0
0
0
10
19
% N
% Pro:
0
10
10
10
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
19
10
19
0
10
0
0
0
10
28
0
28
28
19
% Q
% Arg:
0
10
0
28
0
10
0
19
10
0
10
0
37
0
46
% R
% Ser:
0
0
0
0
0
55
0
19
0
0
10
10
10
0
0
% S
% Thr:
10
10
28
0
0
0
10
0
10
0
0
0
0
0
0
% T
% Val:
10
0
10
10
19
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _