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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APOA4 All Species: 15.76
Human Site: T282 Identified Species: 34.67
UniProt: P06727 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06727 NP_000473 396 45399 T282 R G N L R G N T E G L Q K S L
Chimpanzee Pan troglodytes Q9GJU3 317 36083 M239 L R A R M E E M G S R T R D R
Rhesus Macaque Macaca mulatta XP_001090730 572 65150 T413 R G N L R G N T E G L Q K S L
Dog Lupus familis XP_546510 407 46257 T305 R G K L K D N T A G L H K S L
Cat Felis silvestris
Mouse Mus musculus P06728 395 45011 T282 Q S K V K G N T E G L Q K S L
Rat Rattus norvegicus P02651 391 44438 T282 Q S K L K G N T E G L Q K S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517327 362 41011 A270 R E K L E G N A A E L R Q S L
Chicken Gallus gallus P08250 264 30662 L186 V E E L R K N L A P Y S D E L
Frog Xenopus laevis NP_001088004 369 42412 A282 K V K L Q V N A R D A K Q T L
Zebra Danio Brachydanio rerio O42363 262 30238 V184 E E T K S K V V P M V E A V R
Tiger Blowfish Takifugu rubipres NP_001027893 255 28474 Q177 S V K D L Q A Q L G P Y T D D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.2 64.6 77.8 N.A. 62.1 62.6 N.A. 36.1 23.2 38.3 22.9 23.4 N.A. N.A. N.A. N.A.
Protein Similarity: 100 41.9 66.7 85 N.A. 79.2 79.8 N.A. 57.3 45.2 63.1 40.4 41.4 N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 66.6 N.A. 66.6 73.3 N.A. 46.6 26.6 20 0 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 73.3 N.A. 86.6 86.6 N.A. 60 26.6 53.3 13.3 6.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 19 28 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 10 0 0 0 10 0 0 10 19 10 % D
% Glu: 10 28 10 0 10 10 10 0 37 10 0 10 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 28 0 0 0 46 0 0 10 55 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 55 10 28 19 0 0 0 0 0 10 46 0 0 % K
% Leu: 10 0 0 64 10 0 0 10 10 0 55 0 0 0 73 % L
% Met: 0 0 0 0 10 0 0 10 0 10 0 0 0 0 0 % M
% Asn: 0 0 19 0 0 0 73 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 10 10 0 0 0 0 % P
% Gln: 19 0 0 0 10 10 0 10 0 0 0 37 19 0 0 % Q
% Arg: 37 10 0 10 28 0 0 0 10 0 10 10 10 0 19 % R
% Ser: 10 19 0 0 10 0 0 0 0 10 0 10 0 55 0 % S
% Thr: 0 0 10 0 0 0 0 46 0 0 0 10 10 10 0 % T
% Val: 10 19 0 10 0 10 10 10 0 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _