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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYGL All Species: 35.45
Human Site: Y512 Identified Species: 65
UniProt: P06737 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06737 NP_002854.3 847 97149 Y512 A E K I G E D Y V K D L S Q L
Chimpanzee Pan troglodytes XP_001145433 1033 117244 Y698 A E K I G E D Y V K D L S Q L
Rhesus Macaque Macaca mulatta XP_001102253 847 97088 Y512 A E K I G E D Y V K D L S Q L
Dog Lupus familis XP_537443 822 94051 Y483 A E K I G E D Y V K D L S Q L
Cat Felis silvestris
Mouse Mus musculus Q9ET01 850 97412 Y512 A E K I G E D Y V K D L S Q L
Rat Rattus norvegicus P09811 850 97465 Y512 A E K I G E D Y V K D L S Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515220 790 89928 T452 V K D L S Q L T K L H G F V G
Chicken Gallus gallus NP_989723 857 98547 Y512 A E K I G E D Y V R D L S Q L
Frog Xenopus laevis NP_001088127 855 97869 Y512 A E K I G E D Y V K D L S Q L
Zebra Danio Brachydanio rerio NP_997974 843 97409 F512 A E K I G E D F L T D L F Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XTL9 844 96978 W512 A E K I G D E W P V H L D Q L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SD76 841 95141 W515 K W L K T D K W I T D L D L L
Baker's Yeast Sacchar. cerevisiae P06738 902 103525 Y567 L N D P T E E Y L L D M A K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.9 98.8 91.2 N.A. 94.4 94.3 N.A. 82.6 86 85.6 81.2 N.A. 71.6 N.A. N.A. N.A.
Protein Similarity: 100 81.9 99.2 94.2 N.A. 97.6 97.6 N.A. 87.2 93.9 92.1 90.6 N.A. 83.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 93.3 100 73.3 N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 100 100 86.6 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 44.7 48.5 N.A.
Protein Similarity: N.A. N.A. N.A. 62.3 65.3 N.A.
P-Site Identity: N.A. N.A. N.A. 20 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 77 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 0 0 16 70 0 0 0 85 0 16 0 0 % D
% Glu: 0 77 0 0 0 77 16 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 16 0 0 % F
% Gly: 0 0 0 0 77 0 0 0 0 0 0 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % H
% Ile: 0 0 0 77 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 8 8 77 8 0 0 8 0 8 54 0 0 0 8 0 % K
% Leu: 8 0 8 8 0 0 8 0 16 16 0 85 0 8 93 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 77 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 0 0 0 0 0 0 0 62 0 0 % S
% Thr: 0 0 0 0 16 0 0 8 0 16 0 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 62 8 0 0 0 8 0 % V
% Trp: 0 8 0 0 0 0 0 16 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _