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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYGL
All Species:
41.82
Human Site:
Y76
Identified Species:
76.67
UniProt:
P06737
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06737
NP_002854.3
847
97149
Y76
I
R
T
Q
Q
H
Y
Y
D
K
C
P
K
R
V
Chimpanzee
Pan troglodytes
XP_001145433
1033
117244
Y262
I
R
T
Q
Q
H
Y
Y
D
K
C
P
K
R
V
Rhesus Macaque
Macaca mulatta
XP_001102253
847
97088
Y76
I
R
T
Q
Q
H
Y
Y
D
K
C
P
K
R
V
Dog
Lupus familis
XP_537443
822
94051
Y76
I
R
T
Q
Q
H
Y
Y
E
K
C
P
K
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET01
850
97412
Y76
I
R
T
Q
Q
H
Y
Y
D
K
C
P
K
R
V
Rat
Rattus norvegicus
P09811
850
97465
Y76
I
R
T
Q
Q
H
Y
Y
D
K
C
P
K
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515220
790
89928
M80
A
A
C
F
L
D
S
M
A
T
L
G
L
A
A
Chicken
Gallus gallus
NP_989723
857
98547
Y76
I
R
T
Q
Q
Y
Y
Y
E
R
D
P
K
R
I
Frog
Xenopus laevis
NP_001088127
855
97869
Y76
I
R
T
Q
Q
Y
Y
Y
E
K
D
P
K
R
T
Zebra Danio
Brachydanio rerio
NP_997974
843
97409
Y76
I
R
T
Q
Q
Y
Y
Y
E
K
D
P
K
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTL9
844
96978
Y76
I
R
T
Q
Q
H
Y
Y
E
K
D
P
K
R
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SD76
841
95141
N78
N
E
T
Y
V
H
F
N
K
V
D
P
K
Q
T
Baker's Yeast
Sacchar. cerevisiae
P06738
902
103525
T115
N
K
T
Q
Q
K
F
T
T
R
D
P
K
R
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.9
98.8
91.2
N.A.
94.4
94.3
N.A.
82.6
86
85.6
81.2
N.A.
71.6
N.A.
N.A.
N.A.
Protein Similarity:
100
81.9
99.2
94.2
N.A.
97.6
97.6
N.A.
87.2
93.9
92.1
90.6
N.A.
83.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
0
66.6
73.3
73.3
N.A.
86.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
0
93.3
86.6
93.3
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.7
48.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
65.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
8
0
0
0
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
47
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
39
0
47
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
39
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% H
% Ile:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
0
8
0
0
0
8
0
0
8
70
0
0
93
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
8
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% P
% Gln:
0
0
0
85
85
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
77
0
0
0
0
0
0
0
16
0
0
0
77
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
93
0
0
0
0
8
8
8
0
0
0
0
16
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
24
77
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _