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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLB
All Species:
21.82
Human Site:
S243
Identified Species:
53.33
UniProt:
P06746
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06746
NP_002681.1
335
38178
S243
M
G
V
C
Q
L
P
S
K
N
D
E
K
E
Y
Chimpanzee
Pan troglodytes
XP_001143825
370
41952
S278
M
G
V
C
Q
L
P
S
K
N
D
E
K
E
Y
Rhesus Macaque
Macaca mulatta
XP_001097548
335
38204
S243
M
G
V
C
Q
L
P
S
K
N
D
E
K
E
Y
Dog
Lupus familis
XP_532790
335
38256
S243
M
G
V
C
Q
L
P
S
K
N
D
E
K
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8K409
335
38269
S243
M
G
V
C
Q
L
P
S
E
K
D
G
K
E
Y
Rat
Rattus norvegicus
P06766
335
38308
S243
M
G
V
C
Q
L
P
S
E
N
D
E
N
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424407
335
38413
N243
M
G
V
C
Q
L
P
N
K
E
D
G
T
L
Y
Frog
Xenopus laevis
O57383
334
38275
P242
F
M
G
V
C
Q
L
P
C
E
S
D
Q
D
Y
Zebra Danio
Brachydanio rerio
Q6DRD3
336
38547
K244
V
C
Q
L
Q
K
E
K
E
E
E
E
E
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787665
349
39652
D257
I
I
R
L
P
E
K
D
A
K
E
G
E
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.5
99.4
98.8
N.A.
96.4
95.8
N.A.
N.A.
86.5
83.5
80
N.A.
N.A.
N.A.
N.A.
62.4
Protein Similarity:
100
90.5
99.6
99.4
N.A.
98.8
98.2
N.A.
N.A.
93.1
92.8
88.9
N.A.
N.A.
N.A.
N.A.
79.6
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
N.A.
66.6
6.6
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
N.A.
73.3
26.6
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
10
0
70
10
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
70
10
0
10
0
% D
% Glu:
0
0
0
0
0
10
10
0
30
30
20
60
20
80
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
70
10
0
0
0
0
0
0
0
0
30
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
10
10
10
50
20
0
0
50
0
0
% K
% Leu:
0
0
0
20
0
70
10
0
0
0
0
0
0
10
0
% L
% Met:
70
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
50
0
0
10
0
0
% N
% Pro:
0
0
0
0
10
0
70
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
80
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
60
0
0
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
10
0
70
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _