KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLB
All Species:
35.45
Human Site:
Y49
Identified Species:
86.67
UniProt:
P06746
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06746
NP_002681.1
335
38178
Y49
A
A
S
V
I
A
K
Y
P
H
K
I
K
S
G
Chimpanzee
Pan troglodytes
XP_001143825
370
41952
Y49
A
A
S
V
I
A
K
Y
P
H
K
I
K
S
G
Rhesus Macaque
Macaca mulatta
XP_001097548
335
38204
Y49
A
A
S
V
I
A
K
Y
P
Y
K
I
K
S
G
Dog
Lupus familis
XP_532790
335
38256
Y49
A
A
S
V
I
A
K
Y
P
H
K
I
K
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K409
335
38269
Y49
A
A
S
V
I
A
K
Y
P
H
K
I
K
S
G
Rat
Rattus norvegicus
P06766
335
38308
Y49
A
A
S
V
I
A
K
Y
P
H
K
I
K
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424407
335
38413
Y49
A
A
S
V
I
S
R
Y
P
S
R
I
R
S
G
Frog
Xenopus laevis
O57383
334
38275
Y49
A
A
S
V
I
A
K
Y
P
T
K
I
K
S
G
Zebra Danio
Brachydanio rerio
Q6DRD3
336
38547
I52
I
A
K
Y
P
Q
K
I
K
S
G
T
E
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787665
349
39652
Y60
A
A
S
V
L
A
K
Y
P
T
K
I
K
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.5
99.4
98.8
N.A.
96.4
95.8
N.A.
N.A.
86.5
83.5
80
N.A.
N.A.
N.A.
N.A.
62.4
Protein Similarity:
100
90.5
99.6
99.4
N.A.
98.8
98.2
N.A.
N.A.
93.1
92.8
88.9
N.A.
N.A.
N.A.
N.A.
79.6
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
66.6
93.3
13.3
N.A.
N.A.
N.A.
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
26.6
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
90
100
0
0
0
80
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
90
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
10
0
0
0
80
0
0
10
0
0
0
90
0
0
0
% I
% Lys:
0
0
10
0
0
0
90
0
10
0
80
0
80
0
10
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
90
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% R
% Ser:
0
0
90
0
0
10
0
0
0
20
0
0
0
90
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
20
0
10
0
0
0
% T
% Val:
0
0
0
90
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
90
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _