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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPM3
All Species:
40.4
Human Site:
S283
Identified Species:
80.81
UniProt:
P06753
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06753
NP_001036816.1
284
32819
S283
H
A
L
N
D
M
T
S
I
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001173748
284
32708
S283
H
A
L
N
D
M
T
S
M
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001103704
284
32680
S283
H
A
L
N
D
M
T
S
M
_
_
_
_
_
_
Dog
Lupus familis
XP_864907
284
32692
S283
H
A
L
N
D
M
T
S
I
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P21107
284
32844
S283
H
A
L
N
D
M
T
S
I
_
_
_
_
_
_
Rat
Rattus norvegicus
P58775
284
32818
S283
N
A
L
N
D
I
T
S
L
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19352
284
32758
S283
N
A
L
N
D
I
T
S
L
_
_
_
_
_
_
Frog
Xenopus laevis
Q01173
284
32632
S283
H
A
L
N
D
M
T
S
I
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
P13104
284
32704
S283
H
A
L
N
D
M
T
S
I
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
NP_001027746
284
32727
S283
L
A
L
N
D
M
T
S
I
_
_
_
_
_
_
Fruit Fly
Dros. melanogaster
P49455
518
54567
K283
E
A
F
V
D
L
I
K
G
L
E
P
F
W
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22866
284
32985
G283
S
T
F
Q
E
L
S
G
Y
_
_
_
_
_
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
91.1
91.9
N.A.
98.9
86.6
N.A.
N.A.
86.9
92.6
92.9
92.9
31.4
N.A.
59.1
N.A.
Protein Similarity:
100
96.8
96.8
97.1
N.A.
99.3
96.8
N.A.
N.A.
96.4
97.8
96.4
97.5
41.8
N.A.
75
N.A.
P-Site Identity:
100
88.8
88.8
100
N.A.
100
66.6
N.A.
N.A.
66.6
100
100
88.8
13.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
88.8
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
92
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% G
% His:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
17
9
0
50
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
9
0
84
0
0
17
0
0
17
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
67
0
0
17
0
0
0
0
0
0
% M
% Asn:
17
0
0
84
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
9
84
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
84
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
92
92
92
92
92
92
% _