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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRH
All Species:
13.94
Human Site:
S128
Identified Species:
34.07
UniProt:
P06850
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06850
NP_000747.1
196
21422
S128
L
P
R
R
S
L
D
S
P
A
A
L
A
E
R
Chimpanzee
Pan troglodytes
XP_001155971
124
13538
G77
R
L
G
L
G
T
A
G
E
R
P
R
R
D
N
Rhesus Macaque
Macaca mulatta
XP_001094433
196
21376
S128
L
P
R
R
S
L
D
S
P
A
A
L
A
E
R
Dog
Lupus familis
XP_853760
126
14070
G79
R
W
G
S
R
T
A
G
E
R
P
R
R
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIT0
187
20759
S119
M
P
Q
R
S
L
D
S
R
A
E
P
A
E
R
Rat
Rattus norvegicus
P01143
187
20661
S119
M
P
Q
R
P
L
D
S
S
T
E
L
A
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511883
183
20245
T125
L
P
P
R
P
P
V
T
P
Q
G
A
A
Q
Q
Chicken
Gallus gallus
NP_001116503
167
18203
E110
L
Q
G
S
G
S
P
E
G
D
E
G
A
G
E
Frog
Xenopus laevis
P49188
162
17862
D112
S
P
Y
S
A
Q
E
D
P
T
E
K
A
K
R
Zebra Danio
Brachydanio rerio
NP_001007380
162
18338
A110
D
G
S
Y
A
L
R
A
L
D
S
M
E
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.6
97.9
29
N.A.
79
78
N.A.
56.6
59.6
47.4
47.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.7
98.4
41.8
N.A.
84.1
83.6
N.A.
66.8
64.8
59.1
60.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
66.6
60
N.A.
33.3
13.3
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
6.6
N.A.
80
73.3
N.A.
53.3
13.3
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
20
10
0
30
20
10
70
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
40
10
0
20
0
0
0
20
10
% D
% Glu:
0
0
0
0
0
0
10
10
20
0
40
0
10
40
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
30
0
20
0
0
20
10
0
10
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
40
10
0
10
0
50
0
0
10
0
0
30
0
0
0
% L
% Met:
20
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
60
10
0
20
10
10
0
40
0
20
10
0
0
0
% P
% Gln:
0
10
20
0
0
10
0
0
0
10
0
0
0
10
10
% Q
% Arg:
20
0
20
50
10
0
10
0
10
20
0
20
20
10
50
% R
% Ser:
10
0
10
30
30
10
0
40
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
20
0
10
0
20
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _