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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPL All Species: 22.42
Human Site: S124 Identified Species: 54.81
UniProt: P06858 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06858 NP_000228.1 475 53162 S124 A Q E H Y P V S A G Y T K L V
Chimpanzee Pan troglodytes XP_001149804 475 53143 S124 A Q Q H Y P V S A G Y T K L V
Rhesus Macaque Macaca mulatta XP_001090086 500 56564 A134 A H Q L Y T D A V N N T R V V
Dog Lupus familis XP_534584 471 52540 A121 Q Q H Y P V S A G Y T K L V G
Cat Felis silvestris
Mouse Mus musculus P11152 474 53108 S124 A Q Q H Y P V S A G Y T K L V
Rat Rattus norvegicus Q06000 474 53064 S124 A Q Q H Y P V S A G Y T K L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508587 1005 110074 S591 A Q Q H Y P V S A G Y T K L V
Chicken Gallus gallus P11602 490 55114 S124 A Q Q H Y P V S A A Y T K L V
Frog Xenopus laevis Q641F6 460 51872 N128 A T T V L Y H N A A A K T R K
Zebra Danio Brachydanio rerio Q6DBU8 454 51793 N121 D W N R G A T N M N Y W Q V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 45.4 91.3 N.A. 92.8 92.2 N.A. 41 71.2 28 27.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 66 95.3 N.A. 95.7 96.2 N.A. 43.8 82 43.5 43.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 26.6 6.6 N.A. 93.3 93.3 N.A. 93.3 86.6 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 53.3 26.6 N.A. 100 100 N.A. 100 93.3 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 80 0 0 0 0 10 0 20 70 20 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 10 50 0 0 0 0 10 % G
% His: 0 10 10 60 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 20 60 0 10 % K
% Leu: 0 0 0 10 10 0 0 0 0 0 0 0 10 60 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 20 0 20 10 0 0 0 0 % N
% Pro: 0 0 0 0 10 60 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 70 60 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 10 10 0 % R
% Ser: 0 0 0 0 0 0 10 60 0 0 0 0 0 0 0 % S
% Thr: 0 10 10 0 0 10 10 0 0 0 10 70 10 0 0 % T
% Val: 0 0 0 10 0 10 60 0 10 0 0 0 0 30 80 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 10 70 10 0 0 0 10 70 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _