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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXA
All Species:
15.76
Human Site:
Y497
Identified Species:
28.89
UniProt:
P06865
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06865
NP_000511.2
529
60689
Y497
T
S
D
L
T
F
A
Y
E
R
L
S
H
F
R
Chimpanzee
Pan troglodytes
XP_001175122
529
60636
Y497
T
S
D
L
T
F
A
Y
E
R
L
S
H
F
R
Rhesus Macaque
Macaca mulatta
XP_001092589
529
60742
Y497
T
S
D
L
T
F
A
Y
E
R
L
S
H
F
R
Dog
Lupus familis
XP_544758
529
60532
F497
V
T
N
L
D
S
A
F
K
R
L
T
Q
F
R
Cat
Felis silvestris
Mouse
Mus musculus
P29416
528
60581
F496
T
T
N
I
D
F
A
F
K
R
L
S
H
F
R
Rat
Rattus norvegicus
Q641X3
528
60520
F496
T
T
N
M
D
F
A
F
K
R
L
S
H
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513475
574
64498
Y542
V
R
N
Q
N
D
A
Y
G
R
L
T
Q
H
R
Chicken
Gallus gallus
NP_001025561
526
58930
Y494
V
R
N
L
Q
D
A
Y
V
R
L
A
D
F
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017763
532
60708
F500
T
L
N
A
D
L
A
F
P
R
L
E
E
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8WSF3
660
75468
V622
D
D
H
D
M
D
I
V
P
P
D
V
F
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22492
555
64361
W515
T
Q
R
A
E
D
A
W
P
R
M
H
E
L
R
Sea Urchin
Strong. purpuratus
XP_799340
543
61806
S511
V
T
S
L
D
D
A
S
H
R
L
V
E
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142218
433
49746
G415
R
C
E
L
L
R
R
G
I
Q
A
Q
P
I
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
81.8
N.A.
84.1
82.8
N.A.
54.5
66.1
N.A.
55.2
N.A.
27.7
N.A.
38.3
49.3
Protein Similarity:
100
99.8
99.2
90.7
N.A.
91.1
90.3
N.A.
66.7
78
N.A.
69.9
N.A.
41.6
N.A.
54.2
64.4
P-Site Identity:
100
100
100
40
N.A.
60
60
N.A.
33.3
46.6
N.A.
40
N.A.
6.6
N.A.
26.6
33.3
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
46.6
60
N.A.
53.3
N.A.
6.6
N.A.
40
40
Percent
Protein Identity:
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
77.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
85
0
0
0
8
8
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
24
8
39
39
0
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
24
0
0
8
24
0
0
% E
% Phe:
0
0
0
0
0
39
0
31
0
0
0
0
8
62
0
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
8
39
8
0
% H
% Ile:
0
0
0
8
0
0
8
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% K
% Leu:
0
8
0
54
8
8
0
0
0
0
77
0
0
8
0
% L
% Met:
0
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
47
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
24
8
0
0
8
0
0
% P
% Gln:
0
8
0
8
8
0
0
0
0
8
0
8
16
8
0
% Q
% Arg:
8
16
8
0
0
8
8
0
0
85
0
0
0
8
93
% R
% Ser:
0
24
8
0
0
8
0
8
0
0
0
39
0
0
8
% S
% Thr:
54
31
0
0
24
0
0
0
0
0
0
16
0
0
0
% T
% Val:
31
0
0
0
0
0
0
8
8
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _