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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINE2
All Species:
20.61
Human Site:
S148
Identified Species:
50.37
UniProt:
P07093
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07093
NP_001130000.1
398
44002
S148
V
N
F
E
D
P
A
S
A
C
D
S
I
N
A
Chimpanzee
Pan troglodytes
XP_527841
701
77863
E452
Q
V
D
F
S
E
V
E
R
A
R
F
I
I
N
Rhesus Macaque
Macaca mulatta
XP_001108980
398
43922
S148
V
N
F
E
D
P
A
S
A
C
D
S
I
N
A
Dog
Lupus familis
XP_864163
398
43959
S148
V
S
F
E
D
P
A
S
A
C
D
S
I
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q07235
397
44189
S148
V
N
F
Q
D
P
A
S
A
S
E
S
I
N
F
Rat
Rattus norvegicus
P07092
397
44045
S148
V
N
F
Q
D
P
A
S
A
C
D
A
I
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511446
295
32851
I53
R
P
R
E
N
I
V
I
S
P
H
G
I
A
S
Chicken
Gallus gallus
Q90935
410
46511
A145
N
I
D
F
S
Q
S
A
A
V
A
T
H
I
N
Frog
Xenopus laevis
NP_001086989
395
43908
T147
V
D
F
Q
E
K
N
T
A
A
S
I
I
N
Q
Zebra Danio
Brachydanio rerio
B0UYL8
417
46382
Y164
R
L
Q
Q
W
A
H
Y
Q
S
K
A
D
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.5
97.7
91.7
N.A.
84.9
83.6
N.A.
62.5
34.3
71.8
29
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39
98.4
95.4
N.A.
92.7
92.2
N.A.
67.5
56
83.4
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
86.6
N.A.
73.3
80
N.A.
13.3
6.6
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
93.3
N.A.
86.6
93.3
N.A.
33.3
26.6
60
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
50
10
70
20
10
20
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% C
% Asp:
0
10
20
0
50
0
0
0
0
0
40
0
10
10
0
% D
% Glu:
0
0
0
40
10
10
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
0
60
20
0
0
0
0
0
0
0
10
0
0
20
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
10
% H
% Ile:
0
10
0
0
0
10
0
10
0
0
0
10
80
20
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
40
0
0
10
0
10
0
0
0
0
0
0
60
20
% N
% Pro:
0
10
0
0
0
50
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
10
40
0
10
0
0
10
0
0
0
0
0
10
% Q
% Arg:
20
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% R
% Ser:
0
10
0
0
20
0
10
50
10
20
10
40
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
60
10
0
0
0
0
20
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _