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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPF All Species: 17.27
Human Site: Y278 Identified Species: 31.67
UniProt: P07098 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07098 NP_004181.1 398 45238 Y278 N T S R L D V Y L S H N P A G
Chimpanzee Pan troglodytes XP_521545 398 45247 Y278 N T S R L D V Y L S H N P A G
Rhesus Macaque Macaca mulatta XP_001082289 392 44300 Y278 N A S R L D V Y V S H N P A G
Dog Lupus familis XP_543591 374 43179 S275 H W A Q A A N S G L F Q A F D
Cat Felis silvestris
Mouse Mus musculus Q9CPP7 395 44619 T285 L G H N P A G T S T Q D L F H
Rat Rattus norvegicus P04634 395 44570 H280 R F D V Y L G H N P A G T S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506638 397 45066 T284 V A H A P A G T S V Q N I I H
Chicken Gallus gallus XP_421661 373 42666 V274 M I H W S Q A V K S G E L K A
Frog Xenopus laevis NP_001089697 404 45661 Y286 N M S R V D V Y S S H C P S G
Zebra Danio Brachydanio rerio NP_998569 396 44722 Y278 N M S R T P V Y T A H C P A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46108 394 44883 L288 G A S V N Q N L H F C Q E Y N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67ZU1 418 46029 E297 I D L F L A N E P Q S T S T K
Baker's Yeast Sacchar. cerevisiae P34163 548 62961 K307 Q K I A S Y A K L Y S T T S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 88.9 60 N.A. 77.1 75.6 N.A. 54.5 57.5 57.4 58.5 N.A. 36.6 N.A. N.A. N.A.
Protein Similarity: 100 98.9 92.4 74.3 N.A. 87.9 87.4 N.A. 72.3 73.1 73.7 73.3 N.A. 58 N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 0 N.A. 0 0 N.A. 6.6 6.6 66.6 60 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 20 N.A. 13.3 13.3 N.A. 6.6 6.6 80 66.6 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.4 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 55.7 39.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 8 16 8 31 16 0 0 8 8 0 8 31 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 16 0 0 0 % C
% Asp: 0 8 8 0 0 31 0 0 0 0 0 8 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 0 8 8 0 0 % E
% Phe: 0 8 0 8 0 0 0 0 0 8 8 0 0 16 0 % F
% Gly: 8 8 0 0 0 0 24 0 8 0 8 8 0 0 39 % G
% His: 8 0 24 0 0 0 0 8 8 0 39 0 0 0 16 % H
% Ile: 8 8 8 0 0 0 0 0 0 0 0 0 8 8 0 % I
% Lys: 0 8 0 0 0 0 0 8 8 0 0 0 0 8 8 % K
% Leu: 8 0 8 0 31 8 0 8 24 8 0 0 16 0 0 % L
% Met: 8 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 39 0 0 8 8 0 24 0 8 0 0 31 0 0 8 % N
% Pro: 0 0 0 0 16 8 0 0 8 8 0 0 39 0 0 % P
% Gln: 8 0 0 8 0 16 0 0 0 8 16 16 0 0 0 % Q
% Arg: 8 0 0 39 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 47 0 16 0 0 8 24 39 16 0 8 24 0 % S
% Thr: 0 16 0 0 8 0 0 16 8 8 0 16 16 8 0 % T
% Val: 8 0 0 16 8 0 39 8 8 8 0 0 0 0 16 % V
% Trp: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 39 0 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _