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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX1
All Species:
22.42
Human Site:
Y221
Identified Species:
49.33
UniProt:
P07099
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07099
NP_000111.1
455
52949
Y221
R
L
G
F
Q
E
F
Y
I
Q
G
G
D
W
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093539
455
52943
Y221
R
L
G
F
Q
E
F
Y
I
Q
G
G
D
W
G
Dog
Lupus familis
XP_537235
454
52376
F220
L
R
L
G
F
Q
E
F
Y
I
Q
G
G
D
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9D379
455
52557
Y221
R
L
G
F
Q
K
F
Y
I
Q
G
G
D
W
G
Rat
Rattus norvegicus
P07687
455
52563
Y221
R
L
G
F
Q
K
F
Y
I
Q
G
G
D
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512670
553
63487
Y318
R
L
G
F
Q
E
F
Y
V
Q
G
G
D
W
G
Chicken
Gallus gallus
XP_419386
464
53173
Q222
G
F
H
E
F
Y
A
Q
G
G
D
W
G
W
L
Frog
Xenopus laevis
NP_001085033
456
52088
Q222
G
F
R
E
F
Y
A
Q
G
G
D
W
G
S
L
Zebra Danio
Brachydanio rerio
NP_957362
456
51907
Q220
G
F
T
Q
Y
Y
V
Q
G
G
D
W
G
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394922
446
51273
I219
G
G
D
W
G
S
V
I
A
S
D
M
A
V
L
Nematode Worm
Caenorhab. elegans
NP_504650
452
51442
Y222
R
L
G
Y
N
K
F
Y
L
Q
G
G
D
W
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.2
85
N.A.
83.3
84.1
N.A.
58.7
64
64
61.1
N.A.
N.A.
45.7
46.1
N.A.
Protein Similarity:
100
N.A.
98
90.9
N.A.
92.7
92.7
N.A.
68.9
78.8
79.1
76.9
N.A.
N.A.
62.2
64.6
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
93.3
93.3
N.A.
93.3
6.6
0
0
N.A.
N.A.
0
73.3
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
100
6.6
0
0
N.A.
N.A.
6.6
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
0
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
37
0
55
10
0
% D
% Glu:
0
0
0
19
0
28
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
28
0
46
28
0
55
10
0
0
0
0
0
0
0
% F
% Gly:
37
10
55
10
10
0
0
0
28
28
55
64
37
0
55
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
37
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
55
10
0
0
0
0
0
10
0
0
0
0
0
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
46
10
0
28
0
55
10
0
0
0
0
% Q
% Arg:
55
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
10
0
0
0
19
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
19
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
28
0
64
10
% W
% Tyr:
0
0
0
10
10
28
0
55
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _