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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
4.55
Human Site:
T136
Identified Species:
7.69
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
T136
R
A
V
K
V
F
E
T
F
E
A
K
I
H
H
Chimpanzee
Pan troglodytes
XP_508221
618
67613
T226
R
A
V
K
V
F
E
T
F
E
A
K
I
H
H
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
V110
S
S
E
V
E
I
F
V
D
C
E
C
G
K
T
Dog
Lupus familis
XP_855547
495
55650
R114
Q
I
H
H
L
E
T
R
P
A
Q
R
P
R
A
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
H113
T
F
E
A
K
I
H
H
L
E
T
R
P
A
Q
Rat
Rattus norvegicus
P04177
498
55948
H113
T
F
E
A
K
I
H
H
L
E
T
R
P
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
E173
K
V
L
C
L
F
E
E
K
D
I
N
L
T
H
Chicken
Gallus gallus
P70080
445
51121
D65
S
E
F
E
I
F
V
D
C
D
S
N
R
E
Q
Frog
Xenopus laevis
Q92142
481
55388
F100
R
N
S
E
F
E
I
F
V
D
C
D
S
N
R
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
P109
I
H
H
L
E
T
R
P
S
R
K
P
K
D
G
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
R96
H
I
E
S
R
P
G
R
N
S
K
N
G
T
T
Fruit Fly
Dros. melanogaster
P18459
579
65977
G184
K
A
I
E
T
F
H
G
T
V
Q
H
V
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
E77
G
C
Y
E
V
L
V
E
F
A
E
A
E
D
H
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
K130
E
A
L
R
V
F
Q
K
R
K
V
T
L
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
0
0
N.A.
6.6
6.6
N.A.
20
6.6
6.6
0
0
13.3
N.A.
20
26.6
P-Site Similarity:
100
100
6.6
20
N.A.
13.3
13.3
N.A.
53.3
33.3
26.6
0
0
40
N.A.
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
0
15
0
0
0
0
0
15
15
8
0
15
8
% A
% Cys:
0
8
0
8
0
0
0
0
8
8
8
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
22
0
8
0
15
0
% D
% Glu:
8
8
29
29
15
15
22
15
0
29
15
0
8
15
0
% E
% Phe:
0
15
8
0
8
43
8
8
22
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
8
0
0
0
0
15
0
8
% G
% His:
8
8
15
8
0
0
22
15
0
0
0
8
0
15
36
% H
% Ile:
8
15
8
0
8
22
8
0
0
0
8
0
15
0
0
% I
% Lys:
15
0
0
15
15
0
0
8
8
8
15
15
8
8
0
% K
% Leu:
0
0
15
8
15
8
0
0
15
0
0
0
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
0
0
22
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
8
8
0
0
8
22
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
0
0
15
0
0
0
22
% Q
% Arg:
22
0
0
8
8
0
8
15
8
8
0
22
8
8
8
% R
% Ser:
15
8
8
8
0
0
0
0
8
8
8
0
8
0
8
% S
% Thr:
15
0
0
0
8
8
8
15
8
0
15
8
0
22
15
% T
% Val:
0
8
15
8
29
0
15
8
8
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _