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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
12.42
Human Site:
T269
Identified Species:
21.03
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
T269
T
W
K
E
V
Y
T
T
L
K
G
L
Y
A
T
Chimpanzee
Pan troglodytes
XP_508221
618
67613
T359
T
W
K
E
V
Y
T
T
L
K
G
L
Y
A
T
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
N242
A
C
R
E
Y
L
K
N
F
P
L
L
T
K
Y
Dog
Lupus familis
XP_855547
495
55650
C246
S
L
Y
V
T
H
A
C
R
E
H
L
E
A
F
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
T246
T
L
K
G
L
Y
A
T
H
A
C
R
E
H
L
Rat
Rattus norvegicus
P04177
498
55948
A245
V
T
L
K
G
L
Y
A
T
H
A
C
R
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
T309
T
W
G
T
V
F
R
T
L
K
S
L
Y
T
T
Chicken
Gallus gallus
P70080
445
51121
N197
A
C
R
E
Y
L
K
N
L
P
L
L
T
K
Y
Frog
Xenopus laevis
Q92142
481
55388
N233
A
C
R
E
Y
L
K
N
L
P
L
L
S
K
H
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
S241
L
Y
T
T
H
A
C
S
E
H
L
E
A
F
R
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
F228
P
S
L
A
C
R
Q
F
L
D
S
L
Q
Q
L
Fruit Fly
Dros. melanogaster
P18459
579
65977
T317
T
W
R
S
V
F
K
T
V
Q
D
L
A
P
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
I209
A
C
Q
E
F
N
Y
I
F
P
L
L
Q
Q
N
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
Q263
T
W
G
L
I
Y
R
Q
L
K
A
L
F
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
13.3
13.3
N.A.
26.6
0
N.A.
60
20
20
0
13.3
33.3
N.A.
13.3
46.6
P-Site Similarity:
100
100
20
33.3
N.A.
33.3
6.6
N.A.
66.6
26.6
26.6
13.3
13.3
60
N.A.
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
0
8
0
8
15
8
0
8
15
0
15
22
0
% A
% Cys:
0
29
0
0
8
0
8
8
0
0
8
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
0
0
43
0
0
0
0
8
8
0
8
15
8
0
% E
% Phe:
0
0
0
0
8
15
0
8
15
0
0
0
8
8
8
% F
% Gly:
0
0
15
8
8
0
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
8
8
0
0
8
15
8
0
0
8
15
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
22
8
0
0
29
0
0
29
0
0
0
22
8
% K
% Leu:
8
15
15
8
8
29
0
0
50
0
36
79
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
22
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
29
0
0
0
15
0
% P
% Gln:
0
0
8
0
0
0
8
8
0
8
0
0
15
15
0
% Q
% Arg:
0
0
29
0
0
8
15
0
8
0
0
8
8
0
8
% R
% Ser:
8
8
0
8
0
0
0
8
0
0
15
0
8
0
0
% S
% Thr:
43
8
8
15
8
0
15
36
8
0
0
0
15
8
29
% T
% Val:
8
0
0
8
29
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
36
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
22
29
15
0
0
0
0
0
22
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _