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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBI All Species: 27.27
Human Site: Y32 Identified Species: 46.15
UniProt: P07108 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07108 NP_001073331.1 87 10044 Y32 M L F I Y G H Y K Q A T V G D
Chimpanzee Pan troglodytes XP_001156427 104 11890 Y49 M L F I Y G H Y K Q A T V G D
Rhesus Macaque Macaca mulatta XP_001103096 102 11963 Y32 M L F I Y G R Y K Q A T V G D
Dog Lupus familis XP_849337 87 9960 Y32 M L Y I Y S H Y K Q A T V G D
Cat Felis silvestris
Mouse Mus musculus P31786 87 9982 F32 M L F I Y S H F K Q A T V G D
Rat Rattus norvegicus P11030 87 10009 F32 M L F I Y S H F K Q A T V G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PRL8 86 9626 Y31 M L D V Y S H Y K Q A T V G D
Frog Xenopus laevis NP_001085947 85 9634 L31 E M L E T Y A L Y K Q A T V G
Zebra Danio Brachydanio rerio NP_955902 87 9643 Y32 M L E I Y S L Y K Q A T V G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P42281 86 9538 F32 F L Q L Y A L F K Q A S V G D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O01805 86 9355 F31 L L K L Y A L F K Q G T V G D
Sea Urchin Strong. purpuratus XP_784299 87 9491 F31 L L K I Y S L F K Q V T V G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P57752 92 10367 Y33 L L I L Y G L Y K Q A K F G P
Baker's Yeast Sacchar. cerevisiae P31787 87 10043 Y32 L L E L Y A L Y K Q A T V G D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.6 76.4 85 N.A. 78.1 78.1 N.A. N.A. 75.8 73.5 79.3 N.A. 50.5 N.A. 54 59.7
Protein Similarity: 100 83.6 83.3 96.5 N.A. 91.9 93 N.A. N.A. 88.5 81.6 87.3 N.A. 66.6 N.A. 71.2 70.1
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. 80 0 80 N.A. 53.3 N.A. 53.3 60
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 13.3 80 N.A. 73.3 N.A. 73.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. 44.5 48.2 N.A.
Protein Similarity: N.A. N.A. N.A. 61.9 64.3 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 22 8 0 0 0 79 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 86 % D
% Glu: 8 0 15 8 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 36 0 0 0 0 36 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 29 0 0 0 0 8 0 0 93 8 % G
% His: 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 58 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 15 0 0 0 0 0 93 8 0 8 0 0 0 % K
% Leu: 29 93 8 29 0 0 43 8 0 0 0 0 0 0 0 % L
% Met: 58 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 8 0 0 0 0 0 0 93 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 43 0 0 0 0 0 8 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 79 8 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 8 0 86 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 93 8 0 58 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _