KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEFM
All Species:
6.67
Human Site:
T857
Identified Species:
16.3
UniProt:
P07197
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07197
NP_005373
916
102472
T857
E
K
V
V
V
T
K
T
V
E
K
I
T
S
E
Chimpanzee
Pan troglodytes
Q5R1W8
466
53634
E408
R
K
L
L
E
G
E
E
S
R
I
S
L
P
L
Rhesus Macaque
Macaca mulatta
XP_001106972
919
103102
T860
E
K
V
V
V
T
K
T
V
E
K
I
T
S
E
Dog
Lupus familis
XP_543999
500
55446
T442
T
T
S
K
V
S
S
T
G
L
S
L
K
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P08553
848
95898
K789
D
K
V
V
V
T
K
K
V
E
K
I
T
S
E
Rat
Rattus norvegicus
P23565
505
56097
K447
S
S
A
G
L
S
L
K
K
E
E
E
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508574
942
104269
K883
E
K
I
V
V
T
K
K
V
E
Q
I
T
T
D
Chicken
Gallus gallus
P16053
858
95817
G793
V
S
P
V
D
E
K
G
E
K
V
V
V
T
K
Frog
Xenopus laevis
P35617
470
53654
Y412
G
S
M
F
G
I
G
Y
P
F
S
S
G
S
Y
Zebra Danio
Brachydanio rerio
Q58EE9
444
51231
E386
R
K
L
L
E
G
E
E
S
R
I
T
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.7
97
30.3
N.A.
83.7
30.8
N.A.
63.4
66.1
27.7
25
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
37.1
97.3
41.8
N.A.
86.7
42.5
N.A.
74
74.7
37.9
36
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
20
N.A.
86.6
13.3
N.A.
66.6
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
33.3
N.A.
93.3
33.3
N.A.
93.3
40
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
30
0
0
0
20
10
20
20
10
50
10
10
10
10
50
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
10
10
20
10
10
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
20
40
0
0
0
% I
% Lys:
0
60
0
10
0
0
50
30
10
10
30
0
10
10
10
% K
% Leu:
0
0
20
20
10
0
10
0
0
10
0
10
10
0
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
0
0
0
0
20
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
20
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% R
% Ser:
10
30
10
0
0
20
10
0
20
0
20
20
0
40
0
% S
% Thr:
10
10
0
0
0
40
0
30
0
0
0
10
40
20
0
% T
% Val:
10
0
30
50
50
0
0
0
40
0
10
10
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _